RecruitingPhase 3NCT03647072

PPI Versus Histamine Antagnists as Adjuvant to Chemotherapy

Comparative Clinical and Biochemical Study Evaluating the Effect of Proton Pump I Nhibitors Versus Histamine 2 Receptor Antagonists as an Adjuvant With Chemotherapy in Patients With Non-hodgkin Lymphoma.


Sponsor

Sherief Abd-Elsalam

Enrollment

60 participants

Start Date

Aug 1, 2018

Study Type

INTERVENTIONAL

Conditions

Summary

The study is a Comparative Clinical and Biochemical Study Evaluating the effect of Proton Pump I nhibitors versus histamine 2 Receptor antagonists as an adjuvant with chemotherapy in patients with Non-hodgkin Lymphoma.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • DLBCL Lymphoma subtype --No comorbid disease

Exclusion Criteria4

  • Pregnancy
  • Peptic ulcer
  • Severe cardiac disease
  • Osteoporosis

Interventions

DRUGCHOP

CHOP only

DRUGCHOP Plus Lanzoprazole

CHOP plus Lanzoprazole 60 mg

DRUGCHOP Plus Famotidine

CHOP Plus Famotidine 40 mg


Locations(1)

Sherief Abd-Elsalam

Cairo, Egypt

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NCT03647072


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