RecruitingEarly Phase 1NCT05294367

Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma

Pilot Feasibility Trial of Dietary and Topical Magnesium Replacement or Supplementation in Patients With Lymphoma


Sponsor

Mayo Clinic

Enrollment

60 participants

Start Date

Apr 15, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This early phase I trial investigates the effect of dietary and topical magnesium replacement on magnesium blood levels in patients with lymphoma. Magnesium is an element in the body that is important to cell health. The body cannot make magnesium and it typically comes from the food we eat. In patients who are ill, magnesium is often replaced intravenously (IV) through a vein or by mouth. This study may help researchers find out if being on a magnesium rich diet and using a magnesium lotion on the skin helps to keep magnesium blood levels in an ideal range. This study also investigates side effects and quality of life when receiving different forms of magnesium.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study investigates whether increasing magnesium levels — through diet or topical (skin) application — helps lymphoma patients who have low magnesium levels due to treatment. Low magnesium is a common side effect of some cancer therapies and may cause symptoms like muscle cramps, fatigue, and nerve problems. **You may be eligible if...** - You are 18 or older - You have or have had any type of lymphoma - If you previously received chemotherapy, you are at least 2 months past your last treatment with no new chemotherapy planned - You can eat solid food and liquids normally - You are in good general health **You may NOT be eligible if...** - You are currently on active myelosuppressive chemotherapy - You have significant difficulty eating or swallowing - You have a condition that prevents accurate dietary recall Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMagnesium Chloride-based Lotion

Given topically

OTHERQuality-of-Life Assessment

Ancillary studies

BEHAVIORALSpecial Diet Therapy

Consume magnesium rich foods


Locations(1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

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NCT05294367


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