RecruitingNCT03702907

DC Longitudinal Study on Aging and Specimen Bank

Sponsor

Georgetown University

Enrollment

1,000 participants

Start Date

Jan 1, 2007

Study Type

OBSERVATIONAL

Conditions

Dementia Alzheimer Disease Aging Mild Cognitive Impairment Aging Disorder

Summary

The Georgetown University Memory Disorders Program, part of the Department of Neurology, is conducting pilot studies of the feasibility of various diagnostic tests for Alzheimer's disease, mild cognitive impairment and other neurodegenerative diseases. Further, this study is assessing longitudinal changes in biological, lifestyle, and cognitive assessment collection. The primary goal of this study is to examine the feasibility of biochemical assays, genetic testing, and cognitive and lifestyle assessments in the ante-mortem diagnosis of Alzheimer's disease, mild cognitive impairment and other neurodegenerative diseases. This research involves genetic and cognitive status testing but the findings will not be shared with research subjects. This will be accomplished ex vivo using blood, and/or cerebrospinal fluid (CSF) specimens from patients with a diagnosis of probable Alzheimer's disease, mild cognitive impairment, or other neurodegenerative diseases and from normal controls.

Eligibility

Min Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This is a long-term study following adults in Washington, D.C. as they age, collecting health information, blood samples, and brain imaging data over many years to better understand how neurodegenerative diseases (such as Alzheimer's and Parkinson's) develop — and to build a specimen bank for future research. **You may be eligible if...** - You are 45 years old or older - If you are between 45 and 50 years old, you must have a parent, sibling, or child with a neurodegenerative disease (like Alzheimer's or Parkinson's) **You may NOT be eligible if...** - You are under 45 years old Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Georgetown University Memory Disorders Program

Washington D.C., District of Columbia, United States

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NCT03702907

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