RecruitingNCT03711539

Lifetime Endurance Exercise to Prevent Coronary Artery Disease

Lifetime Endurance Exercise to Prevent Coronary Artery Disease. A Comparison With Late-onset Endurance Training and a Sedentary Lifestyle

Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

1,800 participants

Start Date

Oct 18, 2018

Study Type

OBSERVATIONAL

Conditions

Physical Activity Coronary Artery Disease Lifestyle

Summary

The primary objective of the Master@Heart Trial is to investigate whether lifelong endurance exercise reduces the incidence of non-calcified plaques (both mixed and soft plaques) as compared to late-onset endurance exercise and a non-athletic lifestyle.

Eligibility

Sex: MALEMin Age: 45 YearsMax Age: 70 Years

Inclusion Criteria22

Lifelong endurance athletes:
Initiation of endurance sports before the age of 30 years
Activities at regional, national or international level
Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing
Aged 45-70 years
Involved in competition and high-level training:
more than 10 hours per week for cyclists and triathletes
more than 6 hours per week for runners and rowers.
Late-onset endurance athletes:
Initiation of endurance sports after the age of 30 years and at least 6 months ago
Activities at regional, national or international level
Sports: triathlon, cycling, distance running (1500 metres and longer) and rowing
Aged 45-70 years
Involved in competition and high-level training:
more than 10 hours per week for cyclists and triathletes
more than 6 hours per week for runners and rowers.
Healthy non-athletes
subjects seen in the outpatient clinic for a work-related medical check-up
university alumni
subjects from multisports organisations
history of regular sports practice \<3 hours /week
participation in regular sports with a low dynamic component (e.g. billiards, darts or bowling) \>3 hours /week is allowed