RecruitingNot ApplicableNCT07102797

ActiveGirls: Physical Activity, Hormone Health, and Diabetes Risk in Early Adolescence

Sponsor

Massachusetts General Hospital

Enrollment

40 participants

Start Date

Nov 24, 2025

Study Type

INTERVENTIONAL

Conditions

Insulin Resistance Physical Activity PCOS (Polycystic Ovary Syndrome)Puberty

Summary

This study explores how a physical activity program can affect hormone health and diabetes risk in girls ages 8-12 who may be at higher risk. The study aims to address: * Does the 'ActiveGirls' program meet the needs of girls and families in engaging them to increase physical activity? * What is the trend of markers of diabetes risk and puberty hormones over a 1-year period and how are these levels related to physical activity levels? Participants in this study will either: * Participate in a 'full' intensity intervention that includes educational messages (text/email) as well as health coaching visits to support physical activity over a 6 month period * Participate in a delayed 'lower intensity' intervention that includes only educational messages (text/email) * Participants in both groups will complete at-home activity monitoring, two study visits for check-ups and tests, and surveys

Eligibility

Sex: FEMALEMin Age: 8 Years

Plain Language Summary

Simplified for easier understanding

This study is exploring how physical activity affects hormone health and diabetes risk in adolescent girls, and whether an exercise program can reduce those risks. **You may be eligible if...** - You are an adolescent girl (check the study for the exact age range) - You are willing to participate in physical activity tracking and health assessments - You or your guardian provide consent to participate **You may NOT be eligible if...** - You have a condition that prevents safe participation in physical activity - You are already on medications or treatments that would significantly affect hormone or metabolic measurements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALActiveGirls Physical Activity Program (Full)

Participants in the ActiveGirls Full Intensity intervention group will receive a series of 6 health coaching visits delivered via telemedicine. These visits will address physical activity goal setting within the family. Participants will also receive the ActiveGirls education messaging which will include 3-4 text messages per week (Months 1-6 of their study participation).

BEHAVIORALActiveGirls Physical Activity Program (Delayed Lower Intensity)

Participants in this group will only receive the ActiveGirls education messaging which will include 3-4 text messages per week (Months 7-12 of their study participation)