Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy
Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy - a Randomized, Double-blind, Placebo-controlled Trial
Umeå University
100 participants
Sep 10, 2019
INTERVENTIONAL
Conditions
Summary
Betamethasone is currently given routinely in conjunction with tonsillectomy surgery at the majority of Ear, Nose \& Throat clinics in Sweden. The scientific evidence regarding the effects of betamethasone in adults is limited when it comes to postoperative nausea (PONV), pain and postoperative bleeding.
Eligibility
Inclusion Criteria1
- Signed informed consent Age over 12 years Planned for elective bilateral tonsillectomy
Exclusion Criteria7
- Insulin dependent diabetes mellitus
- NSAID or corticosteroid intolerance
- Pregnancy
- Gastric ulcer
- Immunodeficiency
- Treatment for chronic pain
- Psychiatric disorders
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Interventions
Glucocorticoid
Glucose solution that can be used for injection, but in this case it is used perorally (one ml)
Locations(1)
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NCT03783182