Comparing the Efficacy of Steroid, Acupuncture and Platelet Rich Plasma Injection in Patients with Sciatica
Comparing the Efficacy of Transforaminal Epidural Injections, Acupuncture and Platelet Rich Plasma Injection in Patients with Sciatica Due to Intervertebral Disc Herniation, Spinal Stenosis and Spondylolisthesis
Taipei Medical University Hospital
90 participants
Apr 24, 2019
INTERVENTIONAL
Conditions
Summary
Disc herniation, stenosis of the spine and spondylolisthesis are the common causes of radiculitis in medical practice today, and can cause symptoms of sciatica. Steroid injection, acupuncture and platelet-rich plasma injection are often used interventions for the treatments of sciatica. The investigators will investigate the efficacy and safety of steroid injection, acupuncture and platelet-rich plasma injection for sciatica in this single center, parallel, randomized-controlled clinical trial.
Eligibility
Inclusion Criteria6
- Female or male, 20 to 80 years of age.
- Participants who had dermatome between L3 to S1, or participants whose straight leg raising test was positive, or participants had Meyerding Grade I to II spondylolisthesis or herniated intervertebral disc or spinal stenosis diagnosed by X-rays, Magnetic resonance imaging or computed tomography.
- Participants whose sciatica symptom doesn't have occur time limit.
- Participants who agreed to follow the trial protocol.
- Participants who could complete the study treatment and assessments.
- Participants who had steroid or pain control injection can participate the study after receiving injection more than 3 days.
Exclusion Criteria6
- Participants with severe progressive neurological symptoms (e.g. cauda equina compression).
- Participants who had undergone surgery for lumbar disc herniation within 6 months.
- Participants whose sciatica symptom wasn't caused by lumbar radiculopathy.
- Participants with cardiovascular, liver, kidney, or hematopoietic system diseases, severe psychiatric or psychological disorder, or cancer.
- Women who were pregnant.
- Participants with a pacemaker, metal allergy, or severe fear of needles.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Triamcinolone 1pc + lidocaine 1% 1cc inject at neuritis nerve roots
1.5 inch acupuncture needles insert at acupoints BL23, BL24, BL25 and BL26
Inject investigators Platelet Rich Plasma at neuritis nerve roots
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT03801512