RecruitingNCT03853447
Fibro-inflammatory Progression From Acute to Chronic Pancreatitis
Characterization of Fibro-inflammation During Progression From Acute to Chronic Pancreatitis
Sponsor
Copenhagen University Hospital, Hvidovre
Enrollment
150 participants
Start Date
Feb 14, 2019
Study Type
OBSERVATIONAL
Conditions
Summary
Observational prospective study evaluating the developement of chronic pancreatitis based on imaging modalities as well as biochemical markers of inflammation, fibrosis and oxidative stress.
Eligibility
Min Age: 18 YearsMax Age: 70 Years
Inclusion Criteria3
- Patients with CP (N=50) of any aetiology except gallstone induced CP: CP will be diagnosed based on MANNHEIM criteria .
- Cohort 2: Patients with their first attack of AP of any aetiology except gallstone induced AP (N=50). The revised Atlanta criteria for acute pancreatitis will be used as diagnostic criteria.
- Cohort 3: Patients with RAP (N=50) except gallstone induced RAP. RAP is defined as two or more cases of AP as diagnosed by the revised Atlanta Criteria.
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Interventions
DIAGNOSTIC_TESTDiagnostic imaging
MRI assessments including magnetic resonance cholangiopancreatography (MRCP) and diffusion weighted imaging (DWI) combined with gold standard EUS
Locations(3)
View Full Details on ClinicalTrials.gov
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NCT03853447
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