RecruitingNCT04074720

Prospective Breast Cancer Biospecimen Collection


Sponsor

Thomas Jefferson University

Enrollment

200 participants

Start Date

May 10, 2018

Study Type

OBSERVATIONAL

Conditions

Summary

Tissue will be procured during a standard of care procedure the patient will already be scheduled to undergo. A one time blood draw will be performed at this time and an optional rectal swab for biome analysis may occur. Follow Up will only consist of chart review to determine date of recurrence, metastases, and/or death


Eligibility

Min Age: 18 Years

Inclusion Criteria7

  • Adults \>18 years old at time of consent
  • Subject must be capable to giving informed consent or have an acceptable surrogate capable of giving consent on the subject behalf.
  • Patients with carcinoma in situ or invasive breast cancer
  • Patient must be undergoing one of the following:
  • definitive surgical tumor resection for breast cancer OR
  • placement of a vascular access device as a prelude to neoadjuvant therapy for breast cancer OR
  • neurosurgical resection of a brain metastasis from primary breast cancer.

Exclusion Criteria3

  • \<18 years old
  • Not able to give informed consent and does not have acceptable surrogate capable to giving informed consent.
  • Active drug/alcohol dependence or abuse history

Interventions

PROCEDURETissue Sample collection

Tissue sample collected following standard of care procedure patient was already scheduled to have

OTHERBlood Sample Collection

A one time sample of blood will be collected on day of standard of care procedure

OTHERRectal Swab

optional rectal swab may be collected on day of standard of care procedure


Locations(1)

Sidney Kimmel Cancer Center at Thomas Jefferson University

Philadelphia, Pennsylvania, United States

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NCT04074720


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