BreCLIM-2 - A RCT Investigating Local Treatment for Breast Cancer Liver Metastases

This randomized controlled trial is testing whether surgically removing breast cancer that has spread to the liver (liver metastases), combined with standard cancer treatment, leads to better outcomes than standard cancer treatment alone. This approach is being studied in selected patients with limited liver spread. **You may be eligible if...** - You have a history of breast cancer - You have 1 to 4 liver metastases (cancer spots in the liver) confirmed by biopsy - Your liver metastases are stable or responding to your current cancer treatment - You are suitable for liver surgery and have more than 30% healthy liver tissue remaining after surgery - Your performance status is good (ECOG 0–1) - Bone metastases (if present) are stable or responding to treatment **You may NOT be eligible if...** - You have cancer spread to organs other than the liver and bones - Your primary breast cancer tumor has not been removed - You are pregnant - Your disease is progressing (getting worse) despite cancer treatment Talk to your doctor to see if this trial is right for you.