Liver Metastases Clinical Trials

37 recruiting

Liver Metastases Trials at a Glance

56 actively recruiting trials for liver metastases are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 18 trials, with the heaviest enrollment activity in Amsterdam, Copenhagen, and Houston. Lead sponsors running liver metastases studies include Fudan University, Dana-Farber Cancer Institute, and The Netherlands Cancer Institute.

Browse liver metastases trials by phase

Treatments under study

About Liver Metastases Clinical Trials

Looking for clinical trials for Liver Metastases? There are currently 37 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Liver Metastases trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Liver Metastases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 56 trials

Recruiting
Not Applicable

Incremental Value of Magnetic Resonance Imaging in Selection of Pancreatic Cancer Patients for Surgery

Pancreatic CancerLiver MetastasesPancreatic Neoplasm
University of Aarhus200 enrolled3 locationsNCT05428358
Recruiting
Phase 2

AK104 Plus Radiotherapy Combined With Standard Therapy Versus Standard Therapy as First-Line Treatment for pMMR/MSS CRLM (APSOC)

Colorectal Cancer Liver Metastases (CRLM)
Fudan University73 enrolled1 locationNCT07544784
Recruiting
Phase 1Phase 2

Safety of HRX215 in Patients After Minor and Major Liver Resection

Liver ResectionColorectal Carcinoma Liver Metastases
HepaRegeniX GmbH80 enrolled4 locationsNCT06638502
Recruiting
Phase 2

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Liver MetastasesColorectal Cancer Metastatic
Weill Medical College of Cornell University24 enrolled1 locationNCT06300463
Recruiting
Phase 1Phase 2

Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis

Metastatic MelanomaLiver Metastases
University of Wisconsin, Madison15 enrolled1 locationNCT07281924
Recruiting
Phase 2Phase 3

Tissue Analysis After Tumor Ablation for Liver Metastases Leading to Immediate Retreatment

Liver Metastases
Memorial Sloan Kettering Cancer Center200 enrolled1 locationNCT04143516
Recruiting
Phase 3

Ultra-high Dose Radiation for Liver Metastasis Using MR-guided TReatment With Stereotactic Ablative Single-fraction

Liver Metastases
University Health Network, Toronto114 enrolled1 locationNCT06362395
Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

Breast CancerLiver CancerEsophageal Cancer+35 more
UMC Utrecht8,000 enrolled18 locationsNCT04075305
Recruiting
Phase 2

SCRT(Short Course Radiotherapy) Combined With CAPOX Plus QL1706 for Rectal Cancer Liver Metastases

Locally Advanced Rectal Cancer With Liver Metastases
Fujian Cancer Hospital42 enrolled2 locationsNCT06787183
Recruiting
Not Applicable

Sonoporation and Tumor Microenvironment Response in Colorectal Liver Metastases

Liver Metastases From Colorectal Cancer
Zealand University Hospital48 enrolled2 locationsNCT07365527
Recruiting

AI-Based Prediction of Liver Metastasis in Colorectal Cancer (A Retrospective Study)

Colorectal Cancer Liver Metastases (CRLM)
Tongji Hospital1,500 enrolled1 locationNCT07399236
Recruiting

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Colorectal Cancer MetastaticLiver Transplant SurgeryColon Cancer Liver Metastases
Northwestern University80 enrolled1 locationNCT06698146
Recruiting
Phase 2

REGULUS: MRI-guided Adaptive SABR for Liver Cancers

Liver CancerLiver MetastasesIntrahepatic Cholangiocarcinoma+1 more
Stanford University62 enrolled1 locationNCT07223307
Recruiting
Phase 2

ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases

Liver Metastases
M.D. Anderson Cancer Center120 enrolled1 locationNCT05062317
Recruiting

Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver Metastases

Metastatic Colorectal Carcinoma (mCRC)Colorectal Cancer Liver Metastases (CRLM)
City of Hope Medical Center500 enrolled1 locationNCT07224724
Recruiting
Not Applicable

OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases

Liver MetastasesStereotactic Body Radiation TherapyMRI-guided Treatment
University of Wisconsin, Madison32 enrolled1 locationNCT04020276
Recruiting
Phase 2

FMT+ QL1706+Bevacizumab+ XELOX as First-line Treatment for Advanced MSS-type Colon Cancer With Liver Metastasis

Colon Cancer Liver Metastases
Hua Jiang30 enrolled1 locationNCT06801665
Recruiting
Phase 1Phase 2

Transarterial Chemoembolization (TACE) Plus Bevacizumab for Liver Metastases

CancerMetastatic CancerLiver Metastases
Pardis Noor Medical Imaging and Cancer Center40 enrolled1 locationNCT06311851
Recruiting
Phase 2

Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

Liver MetastasesExtensive-stage Small-cell Lung Cancer
Kamya Sankar39 enrolled3 locationsNCT05588388
Recruiting
Not Applicable

Stereotactic Magnetic Resonance Guided Radiation Therapy

Prostate CancerLung CancerSpine Metastases+10 more
Dana-Farber Cancer Institute397 enrolled2 locationsNCT04115254