RecruitingPhase 4NCT04102566

Optimizing Pain Control in Transurethral Resection of the Prostate


Sponsor

Benaroya Research Institute

Enrollment

50 participants

Start Date

Dec 8, 2017

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to develop a multi-modal protocol for pain management after TURP that minimizes opioid use. The investigators hypothesize this approach will provide non-inferior pain control to the current standard of care which includes opioids as the primary agent. The investigators believe this is an important step in reducing the opioid epidemic in surgical patients.


Eligibility

Sex: MALEMin Age: 18 Years

Inclusion Criteria3

  • Are identified as candidates for TURP
  • Are 18 years of age or greater
  • Are proficient in English

Exclusion Criteria5

  • Have filled an opioid prescription in the last 2 months
  • Have an allergy to a medication included in the protocol
  • Have a history of pelvic radiation
  • Have renal failure (Serum Cr \> 2.0 mg/dl), peptic ulcer disease, history of gastric bypass, cirrhosis, or other contraindication precluding use of NSAID's
  • Have liver failure, hepatitis, or alcohol abuse which precludes use of acetaminophen

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Interventions

DRUGIbuprofen 600 mg

We'll be adding ibuprofen while trying to limit oxycodone use while hospitalized. Patients will not be discharged with a narcotic.

BEHAVIORALEducation

We'll be adding education to patient's post-operative instructions to aid in their pain control management.


Locations(1)

Virginia Mason Medical Center

Seattle, Washington, United States

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NCT04102566


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