Comparative Imaging Assessment of Valvular Heart Disease

This study compares different imaging techniques — including cardiac MRI and echocardiography — for evaluating heart valve disease and other heart conditions. The goal is to determine which imaging method most accurately measures the severity of conditions such as mitral regurgitation, aortic regurgitation, or aortic stenosis, so that doctors can make better treatment decisions. The study also includes patients with a cardiac resynchronization therapy (CRT) device who have not responded well to it, to explore whether better imaging can identify why. You may be eligible if: - You are 18 to 90 years old - You are suspected to have moderate or severe heart valve disease (MR, AR, or AS) based on your clinical history - Or you have an MRI-compatible CRT device and have not responded well to it You may NOT be eligible if: - You have acute heart trauma, aortic dissection, or congenital heart conditions - You have significant disease in multiple heart valves - You have a contraindication to cardiac MRI - You have significant claustrophobia Talk to your doctor to see if this trial is right for you.