RecruitingNCT04190602

Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System

The AcChord Study: A Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System


Sponsor

NeoChord

Enrollment

500 participants

Start Date

Feb 9, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

The objective of this study is to evaluate the 5-year outcomes of participants with degenerative mitral valve disease treated with the NeoChord Artificial Chordae System, Model DS1000 in a post-market setting.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Has Grade III Moderate or Grade IV Severe degenerative or mixed disease mitral valve regurgitation
  • Study procedure completed after 31 December 2016

Exclusion Criteria6

  • Heavily calcified valves
  • Valvular retraction with severely reduced mobility
  • Active bacterial endocarditis
  • Complex mechanism of MR (leaflet perforation, etc.)
  • Significant tethering of leaflets
  • Inflammatory valve disease

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Interventions

DEVICENeoChord Artificial Chordae Delivery System, Model DS1000

The intended use of the device is for the placement of artificial chordae when the natural chordae tendinae have become elongated or ruptured due to degenerative valve disease.


Locations(5)

University of Bonn

Bonn, Germany

CVC Frankfurt

Frankfurt, Germany

University of Mainz

Mainz, Germany

Hippokration Hospital

Athens, Greece

Triemli Hospital

Zurich, Switzerland

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NCT04190602


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