Mitral Valve Insufficiency Clinical Trials

11 recruiting

Mitral Valve Insufficiency Trials at a Glance

12 actively recruiting trials for mitral valve insufficiency are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in New York, Nashville, and Baltimore. Lead sponsors running mitral valve insufficiency studies include NeoChord, Cardiac Dimensions, Inc., and Assistance Publique - Hôpitaux de Paris.

Browse mitral valve insufficiency trials by phase

Treatments under study

About Mitral Valve Insufficiency Clinical Trials

Looking for clinical trials for Mitral Valve Insufficiency? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Mitral Valve Insufficiency trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Mitral Valve Insufficiency clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Heart FailureCardiovascular DiseasesHeart Diseases+3 more
Cardiac Dimensions, Inc.300 enrolled92 locationsNCT03142152
Recruiting
Not Applicable

The ENCIRCLE Trial

Mitral RegurgitationMitral Valve Insufficiency
Edwards Lifesciences900 enrolled68 locationsNCT04153292
Recruiting
Not Applicable

DragonFly EU Pivotal Study

Mitral Valve Insufficiency
Hangzhou Valgen Medtech Co., Ltd168 enrolled1 locationNCT05927441
Recruiting

Clinical Outcomes of Edwards Lifesciences MITRIS RESLILA Mitral Valve in the Asian Population

Mitral Valve Insufficiency
Asan Medical Center200 enrolled1 locationNCT06757049
Recruiting

Study on Efficacy, Safety and Durability of the UniLine Prosthesis in the Treatment of Aortic and Mitral Valve Disease

Diseases of Mitral and Aortic ValvesRheumatic Disorders of Mitral and Aortic ValvesOther Congenital Malformations of Aortic and Mitral Valves+2 more
Closed Joint-Stock Company NeoCor2,000 enrolled1 locationNCT05895487
Recruiting

European Association of Cardiovascular Imaging Multiple and Mixed Valvular Disease Study

Aortic Valve DiseaseHeart Valve DiseasesTricuspid Valve Insufficiency+11 more
Assistance Publique - Hôpitaux de Paris1,500 enrolled1 locationNCT06235385
Recruiting

Prognostic Impact of Imaging Parameters in Patients With Primary Mitral Insufficiency by Prolapse (COHORTE-IM)

Mitral Valve Insufficiency
Lille Catholic University400 enrolled1 locationNCT03962023
Recruiting
Not Applicable

The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study

Mitral Valve Insufficiency
Half Moon Medical30 enrolled5 locationsNCT04343313
Recruiting
Not Applicable

REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial

Coronary Artery DiseaseMitral Valve Insufficiency
Ottawa Heart Institute Research Corporation80 enrolled1 locationNCT04822675
Recruiting

Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System

Mitral RegurgitationMitral Valve InsufficiencyMitral Valve Disease
NeoChord500 enrolled5 locationsNCT04190602
Recruiting
Not Applicable

Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair

Mitral Valve Insufficiency
NeoChord585 enrolled18 locationsNCT02803957
Recruiting
Not Applicable

Personalized Activity Intervention in Rehabilitation After Cardiac Operations (the PACO Trial)

Coronary Artery DiseaseAortic Valve StenosisMitral Valve Insufficiency
Kuopio University Hospital540 enrolled1 locationNCT03470246