RecruitingPhase 2NCT04197297

Brain Imaging Biomarkers in Patients With Brain Metastasis

Imaging Trial of Biomarkers to Guide Individualized Therapy in Patients With Brain Metastasis Receiving Radiotherapy

Sponsor

University Health Network, Toronto

Enrollment

90 participants

Start Date

Oct 5, 2021

Study Type

INTERVENTIONAL

Conditions

Brain Metastases, Adult

Summary

A biomarker is a measurable indicator of the severity or presence of some disease state. In this study, brain metastases patients who will be receiving radiation treatment, will undergo CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) scans prior to and after radiation treatment to measure these biomarkers. This is a single-center phase II study to validate the predictive abilities of biomarkers, in terms of determining how patients will respond to radiation treatment.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at brain imaging markers (using MRI scans) before and after radiation therapy for patients with cancer that has spread to the brain, to better understand how tumors respond to treatment. **You may be eligible if...** - You have cancer confirmed by biopsy that has spread to the brain - At least one brain tumor is larger than 1 cm and does not show signs of bleeding - You are 18 or older - You are scheduled to receive radiation therapy to brain metastases **You may NOT be eligible if...** - You have previously had whole-brain radiation therapy - You have already had radiosurgery to the specific tumor being studied - You cannot undergo an MRI with contrast dye for any reason Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTCT and MRI Scans

CT and MRI scans will occur before and after radiation therapy.

Locations(1)

University Health Network

Toronto, Ontario, Canada

View Full Details on ClinicalTrials.gov

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NCT04197297

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