RecruitingNot ApplicableNCT04229056

COMPuter-assisted Self-training to Improve EXecutive Function

Computer-Assisted Self-Training to Improve Executive Function Versus Unspecific Training in Patients After Stroke, Cardiac Arrest or in Parkinson's Disease: a Randomized Controlled Trial


Sponsor

Bispebjerg Hospital

Enrollment

307 participants

Start Date

Jun 1, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease. The effect of specialized CBCR is compared to generally cognitively stimulating activities on a computer


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria10

  • A diagnose of stroke, cardiac arrest or Parkinson's disease.
  • Aged 18 years or older.
  • Computer and internet access at home.
  • Providing informed consent.
  • Inclusion within 6 months post-stroke
  • Stroke confirmed by clinical findings and imaging, both AIS and ICH is allowed.
  • Initial stroke severity \>/= NIHSS 3.
  • • Inclusion within 6 months post ictus.
  • Clinical diagnosis of PD.
  • Anti-parkinsonian medical treatment (dopaminergic or other).

Exclusion Criteria6

  • Informed consent not provided
  • Other neurological or psychiatric disease which is expected to influence the patient's ability to participate in the trial according to the investigator
  • Not able to participate according to investigator
  • Patients with massive anosognosia for executive dysfunction or patients with no subjective feeling of executive dysfunction (Patient sustains total denial of executive symptoms over time)
  • Patients with severe aphasia, in which it is unclear whether the patient's performance on a neuropsychological test-battery is due to aphasia and not executive dysfunction.
  • • Diagnosis of PD Dementia according to the MDS PD Dementia criteria

Interventions

BEHAVIORALComputer-based cognitive rehabilitation (CBCR)

CBCR are software-programmes for computers which are clinically developed for rehabilitation of various cognitive functions.

BEHAVIORALGeneral computer-based cognitive stimulation

For this trial we have developed a webpage for general cognitive stimulation, which is designed to provide general computer-based cognitive stimulation.


Locations(2)

Bispebjerg Hospital

Copenhagen, Denmark

Rigshospitalet

Copenhagen, Denmark

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NCT04229056


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