Cognitive Dysfunction Clinical Trials

69 recruiting

Cognitive Dysfunction Trials at a Glance

102 actively recruiting trials for cognitive dysfunction are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 53 trials, with the heaviest enrollment activity in Islamabad, Chengdu, and Basel. Lead sponsors running cognitive dysfunction studies include Foundation University Islamabad, Dartmouth-Hitchcock Medical Center, and Beijing Tiantan Hospital.

Browse cognitive dysfunction trials by phase

Treatments under study

About Cognitive Dysfunction Clinical Trials

Looking for clinical trials for Cognitive Dysfunction? There are currently 69 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cognitive Dysfunction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cognitive Dysfunction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 102 trials

Recruiting
Not Applicable

bWell-D Pilot Randomized Controlled Trial

Cognitive DysfunctionDepressive Disorder, Major
University of British Columbia40 enrolled1 locationNCT06546917
Recruiting
Phase 1Phase 2

Stem Cell Therapy for Early Alzheimer's Disease

Cognitive Dysfunction
Paul E Schulz12 enrolled1 locationNCT06775964
Recruiting
Not Applicable

Brain Stimulation and Cognitive Training for MCI

Mild Neurocognitive DisorderCognitive DysfunctionMild Cognitive Impairment (MCI)+2 more
Medical University of South Carolina50 enrolled1 locationNCT07526740
Recruiting

The Role of Neuroinflammation on Neurocognitive Outcome in Cardiac Surgery

Postoperative Neurocognitive DisorderElderly PatientsCardiac Surgery+4 more
Ziekenhuis Oost-Limburg80 enrolled1 locationNCT07200726
Recruiting
Not Applicable

Long COVID Brain Fog: Cognitive Rehabilitation Trial

Cognitive ImpairmentCognitive DysfunctionPost-Acute COVID-19 Syndrome+2 more
University of Alabama at Birmingham30 enrolled1 locationNCT06095297
Recruiting
Not Applicable

taVNS + CCT for Neurocognitive Rehab

Cognitive DysfunctionNeurocognitive FunctionCognitive Complaint+1 more
Medical University of South Carolina20 enrolled1 locationNCT07517237
Recruiting
Not Applicable

Effectiveness of TeleVR App in Cognitive Decline and MCI Patients

Cognitive DysfunctionAlzheimer DiseaseParkinson Disease+2 more
IRCCS Centro Neurolesi Bonino Pulejo480 enrolled1 locationNCT06793735
Recruiting
Not Applicable

Probiotic Impact on Cognitive Performance, and Metabolic Outcomes in Overweight Young Adults With Impaired Glucose Regulation

Cognitive DysfunctionPrediabetes (Insulin Resistance, Impaired Glucose Tolerance)Overweight (BMI > 25)+3 more
Leeds Beckett University70 enrolled1 locationNCT07073781
Recruiting

Venous Congestion And Cognitive Dysfunction After Cardiac Surgery

Intraoperative Venous Congestion And Cognitive Dysfunction After Cardiac Surgery
Zhuan Zhang110 enrolled1 locationNCT07483151
Recruiting

Prediction Model for Postoperative Cognitive Dysfunction in Elderly Cardiac Patients: A Special Disease Cohort Study

Cardiac Diseases Requiring SurgeryPostoperative Cognitive Dysfunction (POCD)
Shanghai Geriatric Medical Center634 enrolled1 locationNCT07483047
Recruiting

Optic Nerve Sheath Diameter and Cognitive Outcomes in Bentall Surgery

Postoperative Cognitive Dysfunction
Bursa Yuksek Ihtisas Training and Research Hospital100 enrolled1 locationNCT07452367
Recruiting
Not Applicable

Cognitive Remediation

Cognitive DysfunctionInflammationAging+3 more
Cutter Lindbergh75 enrolled1 locationNCT07171450
Recruiting
Not Applicable

Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients

Postoperative DeliriumPostoperative Cognitive DeclinePostoperative Cognitive Dysfunction
Heart and Brain Research Group, Germany100 enrolled1 locationNCT04493996
Recruiting
Not Applicable

Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients.

Postoperative DeliriumPostoperative Cognitive DysfunctionPreoperative Stress
Heart and Brain Research Group, Germany125 enrolled1 locationNCT05036538
Recruiting

Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass

Postoperative Cognitive Dysfunction
Bakirkoy Dr. Sadi Konuk Research and Training Hospital106 enrolled1 locationNCT07000461
Recruiting

The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)

Cognitive DysfunctionLiver CirrhosisNeurocognitive Disorders+1 more
University of Malaya230 enrolled1 locationNCT07418008
Recruiting
Not Applicable

Feasibility, Safety, and Preliminary Efficacy of Median Nerve Stimulation for Cognitive Dysfunction in Patients With Acute Traumatic Brain Injury

Traumatic Brain InjuryCognitive Dysfunction
Beijing Tiantan Hospital30 enrolled1 locationNCT07413562
Recruiting

Tennessee Alzheimer's Project

DementiaCognitive DysfunctionAlzheimer Disease+4 more
Vanderbilt University Medical Center1,000 enrolled1 locationNCT05372172
Recruiting
Not Applicable

Audio-Recorded Messages Delivered Via iPad to Prevent Delirium in Hip Fracture Patients

Delirium - PostoperativeDelirium and Post-operative Cognitive Dysfunction (POCD)
Sengkang General Hospital30 enrolled1 locationNCT07396532
Recruiting
Phase 2

ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults

Cognitive DysfunctionAlzheimer DiseaseFatty Acids, Omega-3+3 more
Michal Schnaider Beeri, Ph.D.20 enrolled1 locationNCT07392723