RecruitingNCT04292067

Characterisation of Intestinal Microbiota of Patients With Spondyloarthritis or Rheumatoid Arthritis


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

400 participants

Start Date

Nov 23, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

The primary objective of the study aims to compare the biodiversity of intestinal microbiota between spondylarthritis (SPA) or rheumatoid arthritis (RA) patients and healthy volunteers, by microbiota DNA sequencing in order to further and respond the prior results, which suggested that there is a specific dysbiosis for each of the 2 diseases. A comparative analysis will allow to identify the biomarkers of the specific bacteria.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study looks at the gut microbiome (the community of bacteria living in the intestines) in patients with inflammatory joint diseases — either spondyloarthritis or rheumatoid arthritis — and compares it to healthy people. Researchers want to understand whether gut bacteria play a role in these conditions. **You may be eligible if...** - You are 18 or older - You have been diagnosed with spondyloarthritis or rheumatoid arthritis according to established medical criteria - You are covered by health/social insurance - You can sign the consent form - OR you are a healthy adult with no chronic disease (for the control group) **You may NOT be eligible if...** - You are unable to understand or consent to the study - You have another serious active condition (for healthy volunteers) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALFaecal sampling

Faecal sampling at baseline

BIOLOGICALBlood sampling

Blood sampling at baseline


Locations(1)

Service de Rhumatologie, Hôpital Ambroise Paré, Assistance Publique-Hôpitaux de Paris

Boulogne-Billancourt, France

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NCT04292067


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