RecruitingNCT04306432

Cognitive Function After Radiation Therapy for Primary Brain Tumours


Sponsor

University of Aarhus

Enrollment

300 participants

Start Date

Jan 3, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This study is tracking changes in thinking, memory, and brain function in patients who receive radiation therapy for non-cancerous or low-grade brain tumors. The goal is to better understand how radiation affects cognition so treatments can be improved. **You may be eligible if...** - You are 18 years or older and speak Danish - You are in good enough health to participate in cognitive testing (WHO performance status 0-2) - You have been diagnosed with one of the following brain tumors: anaplastic astrocytoma, diffuse astrocytoma, oligodendroglioma, meningioma, medulloblastoma, pituitary adenoma, or another selected brain tumor type **You may NOT be eligible if...** - You have glioblastoma (the most aggressive type of brain tumor) - You are too unwell to participate in testing (WHO performance status 3-4, or Karnofsky score of 60 or less) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERCognitive tests and Patient Reported Outcomes

Each patient will undergo cognitive tests and questionnaires


Locations(5)

Department of Oncology, Rigshospitalet

Copenhagen, Capital Region, Denmark

Danish Center for Particel Therapy

Aarhus, Region Midt, Denmark

Department of Oncology, Aarhus University Hospital

Aarhus, Region Midt, Denmark

Department of Oncology, Aalborg University Hospital

Aalborg, Region Nord, Denmark

Department of Oncology, Odense University Hospital

Odense, Region Syd, Denmark

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NCT04306432


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