RecruitingNCT04306432

Cognitive Function After Radiation Therapy for Primary Brain Tumours


Sponsor

University of Aarhus

Enrollment

300 participants

Start Date

Jan 3, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This study will assess cognitive function in patients with a primary brain tumour treated with radiation therapy (RT) to generate radio-sensitivity and volume effect parameters for the development of cognitive dysfunction. All types of brain tumours apart from glioblastoma will be included.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria4

  • years or older and Danish speaking.
  • Performance status WHO 0-2
  • Capable of cooperating on testing
  • Tumour histology (WHO 2016 classification) of the following types: anaplastic astrocytoma (IDH mutant), diffuse astrocytoma (IDH-mutant), gemistocytic astrocytoma (IDH mutant), diffuse astrocytoma (NOS), oligodendroglioma, meningioma, medulloblastoma (NOS), pituitary adenoma, other brain tumours including skull base sarcomas

Exclusion Criteria2

  • Glioblastoma
  • Performance status 3-4 (Karnofsky Performances of 60 or less)

Interventions

OTHERCognitive tests and Patient Reported Outcomes

Each patient will undergo cognitive tests and questionnaires


Locations(5)

Department of Oncology, Rigshospitalet

Copenhagen, Capital Region, Denmark

Danish Center for Particel Therapy

Aarhus, Region Midt, Denmark

Department of Oncology, Aarhus University Hospital

Aarhus, Region Midt, Denmark

Department of Oncology, Aalborg University Hospital

Aalborg, Region Nord, Denmark

Department of Oncology, Odense University Hospital

Odense, Region Syd, Denmark

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NCT04306432


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