RecruitingNCT04330651

Post-Surgery Extracorporeal Life Support

Outcomes' Predictors in Post-Surgery Extracorporeal Life Support


Sponsor

University of Florence

Enrollment

500 participants

Start Date

Jan 1, 2004

Study Type

OBSERVATIONAL

Conditions

Summary

Extracorporeal Life Support (ECLS) may provide pulmonary and circulatory support for patients with acute heart failure refractory to conventional medical therapy. However, indications and effectiveness of ECLS engagement post-surgery remains a concern. The investigators sought to analyze indications, modality and outcomes of PS-ECLS, to identify predictors of early and midterm survival after PS-ECLS. The investigators have recorded prospectively, and analysed data of 209 consecutive PS-ECLS patients between January 2004 and December 2018. Demographic and clinical data before, during and after PS-ECLS were collected and their influence on hospital mortality and outcomes (early and midterm) will analyse. Multivariate analysis of pre PS-ECLS implantation factors (as age, female sex , insulin-dependent diabetes, pulmonary hypertension, STS, type of surgical procedure data, pre-ECLS blood lactate level) will be made for identify prognostic risk factors of in-hospital mortality. Overall survival will be analysed, at 6 months,1-year and 5-years, respectively and the factors influencing mild/term outcome will be investigated.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria1

  • Patients underwent cardiac surgery

Exclusion Criteria1

  • Age < 18 years

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Interventions

PROCEDUREECLS

Emergency application of Extracorporeal Life Support in post-surgical patients


Locations(1)

Massimo Bonacchi

Florence, Italy

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NCT04330651


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