Prospective Multicenter Randomized Comparative Study of the Treatment of de Novo Stenosis in Chron's Disease.

This study is comparing different treatments for people with Crohn's disease who have developed a new narrowing (stenosis) in their intestine — a fibrous blockage that makes it hard for food and waste to pass through. Researchers are comparing endoscopic (non-surgical) treatments, such as dilation or stenting, against surgery to find out which works best. **You may be eligible if...** - You are between 18 and 80 years old - You have Crohn's disease with a new fibrous narrowing of the intestine confirmed by imaging and colonoscopy - Your narrowing causes symptoms of intestinal blockage - Your narrowing is accessible by colonoscopy and is less than 10 cm long - You have no more than 2 narrowings - Standard medical treatments have not resolved your problem **You may NOT be eligible if...** - Your narrowing is complicated by an abscess, fistula, or severe active inflammation - You have had a stent or dilation for this narrowing within the last year - You are pregnant or breastfeeding - You have severe blood clotting problems - Your narrowing cannot be reached by colonoscopy Talk to your doctor to see if this trial is right for you.