RecruitingNot ApplicableNCT04368702

CONFIRM: Magnetic Resonance Guided Radiation Therapy

Clinical Onboard Utilization of Image Guided Radiation Therapy With Magnetic Resonance (CONFIRM): A Master Protocol


Sponsor

Brigham and Women's Hospital

Enrollment

70 participants

Start Date

May 1, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating MRI-guided radiation therapy — a technology that uses real-time MRI imaging during radiation treatment to precisely target tumors and avoid nearby healthy tissue. The trial is open to patients with many different types of cancer who need radiation therapy. **You may be eligible if:** - You have a confirmed cancer that requires radiation treatment - You are 18 years or older - You are in reasonably good health (ECOG performance status 0–2) - You are willing and able to sign informed consent **You may NOT be eligible if:** - You have had a severe allergic reaction to gadolinium-based MRI contrast dye (only relevant if contrast will be used) - You have severe claustrophobia or significant anxiety that prevents MRI scanning - You are physically unable to undergo MRI (e.g., due to implanted metal devices or pacemakers) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONViewray MRIdian® Linac

MR-image guided radiation will be administered per disease site standards.


Locations(2)

Brigham & Women's Hospital

Boston, Massachusetts, United States

Dana Farber Cancer Institute

Boston, Massachusetts, United States

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NCT04368702


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