Entire-body PET Scans for Multiple Sclerosis

This study uses a new type of PET scan that can image the entire body at once to study inflammation in people with multiple sclerosis (MS). The goal is to see if this advanced imaging can better detect disease activity throughout the body, including the brain and spinal cord, compared to standard imaging. **You may be eligible if...** - You have a confirmed diagnosis of multiple sclerosis (MS), diagnosed by a neurologist - OR you are a healthy volunteer willing to participate for comparison - You are able to lie still on a scanner bed for 10 to 20 minutes **You may NOT be eligible if...** - You have other significant neurological or psychiatric illnesses unrelated to MS - You are pregnant or breastfeeding - You have diabetes or other metabolic/endocrine disorders - You have an active infection - You have a history of metastatic or invasive cancer - You have had recent surgery, chemotherapy, or radiation therapy Talk to your doctor to see if this trial is right for you.