RecruitingPhase 3NCT04415983

Study of Nitazoxanide (NTZ) for Helicobacter Pylori in Children

Study of Novel Triple Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori in Children


Sponsor

Tanta University

Enrollment

100 participants

Start Date

Jun 1, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

Study of Nitazoxanide (NTZ) based therapeutic regimens for Helicobacter pylori in children


Eligibility

Max Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This Phase 3 study tests nitazoxanide (NTZ)-based antibiotic combinations as a new treatment approach for Helicobacter pylori infection in children — a stomach bacterium that can cause ulcers and, if untreated, long-term digestive problems. Standard H. pylori treatments sometimes fail, and researchers are testing whether NTZ-based regimens offer a more effective alternative. Children with a confirmed positive Helicobacter pylori test who have not previously been treated for the infection are eligible. Participation involves taking the assigned antibiotic regimen and follow-up testing to check whether the infection was successfully cleared. This summary was prepared as patient-facing educational content using AI assistance.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNitazoxanide

Nitazoxanide twice daily

DRUGClarithromycin

Klacid twice daily

DRUGMetronidazole

Metronidazole twice daily

DRUGProton pump inhibitor

Omeprazoe twice daily


Locations(1)

Sherief Abd-Elsalam

Tanta, Egypt

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NCT04415983


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