RecruitingPhase 2NCT04427709

Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity

Generate and Test the Reliability of a Pharmacodynamic Model of Oxytocin on Pupillary Hippus as a Measure of Central Nervous System Activity


Sponsor

Wake Forest University Health Sciences

Enrollment

38 participants

Start Date

Nov 30, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to evaluate the effects of oxytocin (naturally occurring hormone) given by an intramuscular (IM; into the muscle) injection, has on your parasympathetic nervous system. The parasympathetic nervous system is the part of the involuntary nervous system that is sometimes called the "rest and digest" system; the parasympathetic system conserves energy as it slightly slows the heart rate, increases intestinal and gland activity, and relaxes sphincter muscles in the gastrointestinal tract.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Oxytocin and a drug called Placebo for people with chronic pain and osteoarthritis, knee. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGOxytocin

Intramuscular injection of Oxytocin (Pitocin®)

DRUGPlacebo

Intramuscular placebo injection


Locations(1)

Wake Forest Baptist Health

Winston-Salem, North Carolina, United States

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NCT04427709


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