RecruitingPhase 2NCT06544291

Combined THC and CBD for OUD and Chronic Pain

Combination of THC and CBD as Novel Treatment for Co-Occurring Opioid Use Disorder and Chronic Pain


Sponsor

Yale University

Enrollment

147 participants

Start Date

Oct 22, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The primary objective of this phase 2 study is to investigate the therapeutic potential of orally administered combined delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) in relieving both pain and cue-induced opioid craving in people with co-occurring opioid use disorder (OUD) and chronic pain who are undergoing methadone therapy.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called CBD 300mg, a drug called CBD 600mg, and others for people with chronic pain and opioid-use disorder. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCBD 300mg

3 Nantheia™ (100mg) softgel capsules and 3 placebo (0mg) softgel capsules will be administered to participants on one of the three test session days.

DRUGCBD 600mg

6 Nantheia™ (100mg) softgel capsules will be administered to participants on one of the three test session days.

DRUGPlacebo 0mg

6 placebo (0 mg) softgel capsules will be administered to participants on one of the three test session days.


Locations(1)

Connecticut Mental Health Center

New Haven, Connecticut, United States

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NCT06544291


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