RecruitingNot ApplicableNCT04432025

Medication Following Bariatric Surgery for Type 2 Diabetes Mellitus

Sponsor

Imperial College London

Enrollment

150 participants

Start Date

Apr 1, 2021

Study Type

INTERVENTIONAL

Conditions

Obesity Type 2 Diabetes

Summary

The aim of this study is to investigate the continued usage of standard diabetes medications in the post operative period following bariatric surgery to determine whether this approach may improve long term diabetes control. At present, the standard of treatment in patients with type 2 diabetes is that all medication is stopped in the immediate postoperative period and only re-started if symptoms of diabetes re-emerge. Although a large proportion of patients with diabetes will initially go in to remission, 80% experience relapse within five years. This study is needed to determine whether continuing medications is not only safe but will improve long term outcomes for patients with diabetes.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how to safely adjust diabetes medications after bariatric (weight loss) surgery, to avoid dangerous drops in blood sugar and blood pressure. **You may be eligible if...** - You have Type 2 diabetes and are scheduled for bariatric surgery - Your BMI is above 30 - You meet standard guidelines for bariatric surgery **You may NOT be eligible if...** - You were hospitalized in the past 30 days - You frequently experience low blood sugar (hypoglycemia) or low blood pressure - You have had bariatric surgery before - You are pregnant - You have a medical reason that rules out bariatric surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBariatric surgery + goal directed medical therapy

Patients will undergo bariatric surgery (RYGB or SG) with goal directed medical therapy titrated to specific end points for BP, HbA1c and lipids

PROCEDUREBariatric surgery

Patients will undergo bariatric surgery (RYGB or SG) with usual care for diabetes mellitus undertaken by their primary care provider/general practitioner