RecruitingNCT04455867

The Sunnybrook Type 2 Diabetes Study


Sponsor

Sunnybrook Health Sciences Centre

Enrollment

500 participants

Start Date

Dec 21, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from the neighbouring University Health Network Toronto Rehabilitation Institute Cardiac Rehabilitation Program.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at the relationship between blood sugar problems and brain health in people who are at risk for or already have Type 2 diabetes. Researchers want to understand how blood sugar control affects the brain and whether lifestyle changes make a difference. **You may be eligible if:** - You are 18 or older and can communicate in English - You have been diagnosed with Type 2 diabetes, OR you have higher-than-normal blood sugar (pre-diabetes), OR your HbA1c (a blood sugar measure) is elevated **You may NOT be eligible if:** - You are pregnant - You currently have cancer - You have been diagnosed with bipolar disorder or schizophrenia - You have a neurological or neurodegenerative condition (such as Parkinson's or Alzheimer's) - You have a current or recent (within 5 years) substance use disorder (excluding nicotine) - You scored poorly on a basic memory and thinking test - For the brain scan sub-study: you have a pacemaker or other MRI-incompatible devices, or significant lung disease Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALDiabetes Exercise and Healthy Lifestyle Program

The program combines exercise, education and healthy lifestyle behaviour changes. Participants will begin the program with a cardiopulmonary exercise assessment. Then the team will create a personalized program of exercise based on functional abilities and personal goals. Participants will attend 1 supervised exercise class a week, which includes a warm-up and stretching routine, aerobic exercise (walking, stationary cycling or elliptical machine), resistance training and an educational session. This program also offers peer-to-peer support and encourages participants to carry out their own exercise program at home 4 more times per week and to keep a weekly exercise diary to help them with their progress.

OTHEROutpatient care

Participants receive usual care from outpatient services, which may include Endocrinology, Family Medicine, or Diabetes Education


Locations(1)

Sunnybrook Research Institute

Toronto, Ontario, Canada

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NCT04455867


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