Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

This study is testing whether combining testosterone therapy with locomotor (walking) training can improve bone density and muscle mass in men with spinal cord injury who also have low testosterone levels. Both low testosterone and reduced activity after spinal cord injury contribute to muscle loss and bone thinning. **You may be eligible if:** - You are a man over 18 with a spinal cord injury that occurred at least 60 days ago - Your injury involves upper motor neuron signs (spasticity or high muscle tone) - Your testosterone levels are below normal - You have at least one symptom of low testosterone (fatigue, low libido, muscle loss, bone loss, depression, etc.) - You have difficulty walking or walk slowly and rely on assistive devices **You may NOT be eligible if:** - You have prostate or breast cancer - You have very low red blood cell counts (severe anemia) or blood clotting problems - You have uncontrolled heart disease or severe liver disease - Your injury level or severity makes you ineligible based on specific clinical criteria - You are already on testosterone therapy Talk to your doctor to see if this trial is right for you.