Nervous System Diseases Clinical Trials

14 recruiting

Frequently Asked Questions

Common questions about Nervous System Diseases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled1 locationNCT07326566
Recruiting

Collection of Biological Samples From Patients With Rare Neurological Diseases

Nervous System Diseases
University Hospital, Toulouse1,000 enrolled1 locationNCT04698421
Recruiting
Not Applicable

Treating Depression on a Day-to-day Basis: Development of a Tool for Physicians Based on a Smartphone Application

Brain DiseasesCentral Nervous System DiseasesDepression+2 more
Centre Hospitalier Charles Perrens, Bordeaux200 enrolled1 locationNCT03678194
Recruiting
Phase 3

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

DementiaBrain DiseasesCentral Nervous System Diseases+6 more
Eli Lilly and Company1,500 enrolled141 locationsNCT05508789
Recruiting
Phase 1

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NeoplasmsNeoplasms by SiteBrain Diseases+30 more
M.D. Anderson Cancer Center24 enrolled3 locationsNCT03911388
Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting

Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease

COPDSympathetic Nervous System DiseasesCatecholamine; Overproduction
RWTH Aachen University135 enrolled1 locationNCT04849806
Recruiting
Not Applicable

Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity

Brain DiseasesCentral Nervous System DiseasesParkinson Disease+7 more
University Hospital, Bonn130 enrolled1 locationNCT07324330
Recruiting

Cardiac Assessment for Recurrent Stroke Risk Evaluation in Atrial Fibrillation

Brain DiseasesCentral Nervous System DiseasesAtrial Fibrillation+11 more
Insel Gruppe AG, University Hospital Bern500 enrolled1 locationNCT06954610
Recruiting
Not Applicable

Study to Evaluate the Efficacy and Safety of ATNC-MDD V1(TMS With Cognitive Training) in Mild Alzheimer's Dementia

DementiaBrain DiseasesCentral Nervous System Diseases+5 more
Advanced Technology & Communications158 enrolled11 locationsNCT06088121
Recruiting

Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures, Third Wave

Heart FailureAsthmaDepressive Disorder+13 more
Universitätsklinikum Hamburg-Eppendorf240 enrolled1 locationNCT06890208
Recruiting
Not Applicable

Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

Cardiovascular DiseasesCentral Nervous System DiseasesStroke+2 more
Jorge Gonzalez-Martinez10 enrolled1 locationNCT06303869
Recruiting
Not Applicable

Neurologic Stem Cell Treatment Study

Cognitive ImpairmentDementiaTraumatic Brain Injury+23 more
MD Stem Cells500 enrolled3 locationsNCT02795052
Recruiting
Not Applicable

Slow-SPEED-NL: Slowing Parkinson's Early Through Exercise Dosage-Netherlands

Brain DiseasesCentral Nervous System DiseasesParkinson Disease+8 more
Radboud University Medical Center110 enrolled1 locationNCT06193252
Recruiting

Application of AI Technology for the Diagnosis and Treatment of Geriatric Diseases

Alzheimer DiseaseParkinson DiseaseNervous System Diseases+1 more
Qilu Hospital of Shandong University460 enrolled1 locationNCT06295263
Recruiting
Phase 2

Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

Central Nervous System DiseasesGenital Diseases, MaleHypogonadism+17 more
North Florida Foundation for Research and Education21 enrolled2 locationsNCT04460872
Recruiting
Not Applicable

MUSic Therapy In Complex Specialist Neurorehabilitation

Traumatic Brain InjuryStrokeSpinal Cord Injuries+6 more
University College, London75 enrolled1 locationNCT05777499
Recruiting
Phase 2

Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)

InsomniaCognitive DysfunctionAlzheimer Disease+6 more
University of Virginia144 enrolled1 locationNCT05565833
Recruiting
Not Applicable

A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China

Cognitive ImpairmentBrain DiseasesCentral Nervous System Diseases+7 more
Zhejiang University1,200 enrolled1 locationNCT05886114
Recruiting
Phase 3

Non-inferiority Study of Rituximab Compared to Ocrelizumab in Relapsing MS

Demyelinating DiseasesMultiple SclerosisNervous System Diseases+3 more
Amsterdam UMC, location VUmc200 enrolled1 locationNCT05834855