Nervous System Diseases Clinical Trials

42 recruiting

Nervous System Diseases Trials at a Glance

59 actively recruiting trials for nervous system diseases are listed on ClinicalTrialsFinder across 6 cities in 26 countries. The largest study group is Not Applicable with 27 trials, with the heaviest enrollment activity in London, Pittsburgh, and Houston. Lead sponsors running nervous system diseases studies include Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Kessler Foundation, and Tao Xin.

Browse nervous system diseases trials by phase

Treatments under study

About Nervous System Diseases Clinical Trials

Looking for clinical trials for Nervous System Diseases? There are currently 42 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Nervous System Diseases trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Nervous System Diseases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 59 trials

Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled4 locationsNCT07326566
Recruiting
Not Applicable

Functional Near-infrared Spectroscopy in Unconscious Patients

Nervous System DiseasesHealthy Subjects
Emanuela Keller30 enrolled2 locationsNCT04746820
Recruiting

Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology

Nervous System Diseases (C10 Unique ID D009422)
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT06203626
Recruiting
Not Applicable

Intra-arterial Thrombolysis for Acute Ischemic Stroke With Medium Vessel Occlusion

Brain DiseasesStrokeCerebrovascular Disorders+5 more
The Second Hospital of Anhui Medical University282 enrolled6 locationsNCT07185022
Recruiting
Phase 1

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NeoplasmsNeoplasms by SiteBrain Diseases+30 more
M.D. Anderson Cancer Center24 enrolled3 locationsNCT03911388
Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Phase 3

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

DementiaBrain DiseasesCentral Nervous System Diseases+6 more
Eli Lilly and Company1,500 enrolled141 locationsNCT05508789
Recruiting
Not Applicable

Mixed Reality and Virtual Reality Technology With Mirror Therapy for Stroke Rehabilitation

Central Nervous System DiseasesStrokeCerebrovascular Disorders
Chang Gung Memorial Hospital45 enrolled1 locationNCT05903235
Recruiting

Collection of Biological Samples From Patients With Rare Neurological Diseases

Nervous System Diseases
University Hospital, Toulouse1,000 enrolled1 locationNCT04698421
Recruiting
Not Applicable

Treating Depression on a Day-to-day Basis: Development of a Tool for Physicians Based on a Smartphone Application

Brain DiseasesCentral Nervous System DiseasesDepression+2 more
Centre Hospitalier Charles Perrens, Bordeaux200 enrolled1 locationNCT03678194
Recruiting
Not Applicable

Basic and Clinical Study of Cardiac Ganglion Catheter Ablation for the Treatment of Significant Bradycardia

Autonomic Nervous System DiseasesSymptomatic Bradycardia
Beijing Anzhen Hospital188 enrolled1 locationNCT07468383
Recruiting

Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease

COPDSympathetic Nervous System DiseasesCatecholamine; Overproduction
RWTH Aachen University135 enrolled1 locationNCT04849806
Recruiting
Not Applicable

Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity

Brain DiseasesCentral Nervous System DiseasesParkinson Disease+7 more
University Hospital, Bonn130 enrolled1 locationNCT07324330
Recruiting
Not Applicable

Effects of the COTID (Community Occupational Therapist in Dementia) Program and Usual Occupational Therapy Care on Recurrence of Falls at 12 Months in Elderly People With Neurocognitive Disorders Who Had Been Hospitalized for Falls, After Their Return Home

Nervous System Diseases
University Hospital, Limoges76 enrolled1 locationNCT06237218
Recruiting
Not Applicable

Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Upper Limb Recovery in Patients With Stroke

Brain DiseasesCentral Nervous System DiseasesStroke+2 more
King Saud University100 enrolled1 locationNCT07288385
Recruiting
Not Applicable

Gravity Stent-Retriever System For Reperfusion Of Large Vessel Occlusion Stroke Trial

Cardiovascular DiseasesBrain DiseasesCentral Nervous System Diseases+5 more
Gravity Medical Technology, INC100 enrolled11 locationsNCT06249776
Recruiting
Phase 4

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting

Cardiac Assessment for Recurrent Stroke Risk Evaluation in Atrial Fibrillation

Brain DiseasesCentral Nervous System DiseasesAtrial Fibrillation+11 more
Insel Gruppe AG, University Hospital Bern500 enrolled1 locationNCT06954610
Recruiting
Not Applicable

Clinical Evaluation of EEG Device for the Triage of Stroke Patients in the Ambulance

Cardiovascular DiseasesBrain DiseasesCentral Nervous System Diseases+5 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)275 enrolled1 locationNCT06871969
Recruiting
Not Applicable

Video Call Assisted Assessment of Acute Stroke

Brain DiseasesCentral Nervous System DiseasesStroke+3 more
University of Southern Denmark512 enrolled1 locationNCT06570681