Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
Boston Children's Hospital
200 participants
Apr 1, 2021
INTERVENTIONAL
Conditions
Summary
This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.
Eligibility
Inclusion Criteria3
- Age 0 to 21 years
- Admitted to Boston Children's Hospital after experiencing first lifetime BRUE, or with dysphagia symptoms such that they would be at risk for BRUE or other symptoms of swallowing difficulty
- Have had videofluoroscopic swallow study performed or might have future videofluoroscopic swallow study performed.
Exclusion Criteria4
- Any pre-existing medical diagnoses that exclude brief resolved unexplained event diagnosis including seizure disorders and cyanotic congenital heart disease
- Any nasal/pharyngeal/esophageal anomalies that might affect safe placement of the pharyngeal motility catheter
- Children fed exclusively by enteral tube
- Allergy to rice cereal or Gelmix thickener, which will be used to adjust liquid viscosity
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Interventions
Thin liquid swallows of formula or breastmilk or other liquid
Slightly thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix
Mildly thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix
Moderately thick liquid swallows of formula thickened with rice cereal or breastmilk or other liquid thickened with Gelmix
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04504227