RecruitingNCT06821399

Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus


Sponsor

Yufan Wang

Enrollment

2,920 participants

Start Date

Feb 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study aims to integrate clinical indicators and features of fundus images, combined with metabolomics, to construct an early warning model for diabetic retinopathy (DR) in type 2 diabetes. By combining clinical indicators with metabolomics, the investigators aim to establish a precise DR typing model based on the age of diabetes onset (early-onset diabetes, late-onset diabetes) and based on the coexistence with two types of diabetic macrovascular complications. A multidisciplinary collaboration will be conducted for comprehensive management of DR to control the progression of moderate-stage DR. Cloud-based patient rooms combined with continuous glucose monitoring (CGM) will further explore the role of integrated diabetes retinopathy ward management models in the management of patients undergoing diabetes retinopathy surgery, pioneering a new model for the management of advanced DR.


Eligibility

Min Age: 20 YearsMax Age: 79 Years

Plain Language Summary

Simplified for easier understanding

This study tests an improved system for screening and managing diabetic retinopathy (eye disease caused by diabetes) in people with type 2 diabetes. It aims to evaluate how well this optimized system works in detecting and treating eye complications earlier. **You may be eligible if...** - You have been diagnosed with type 2 diabetes (per Chinese guidelines) - You are between 20 and 79 years old - You have full cognitive and literacy abilities - You are willing to participate voluntarily **You may NOT be eligible if...** - You have type 1 or another type of diabetes - You have severe heart, lung, liver, or kidney disease - You have dementia, speech disorders, or mental confusion - You are bedridden or unable to care for yourself Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTFundus Examination

Performing fundus photography on patients to assess the progression of diabetic retinopathy (DR).

DIAGNOSTIC_TESTMetabolomics analysis

Conduct metabolomics testing at enrollment.


Locations(3)

The first hosptial of lanzhou university

Lanzhou, China

Shanghai general hosptial

Shanghai, China

The forth people's hosptial of shenyang

Shenyang, China

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NCT06821399


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