RecruitingNot ApplicableNCT04553523

Hydrus® Microstent New Enrollment Post-Approval Study

The Hydrus® Microstent New Enrollment Post-Approval Study: A Prospective, Non-Randomized, Multicenter, Single Arm, Clinical Trial


Sponsor

Alcon Research

Enrollment

545 participants

Start Date

Aug 25, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this post-approval study is to evaluate the rate of Hydrus Microstent malposition and associated clinical sequelae occurring within 24 months post-operation. Qualified subjects will undergo uncomplicated cataract surgery with placement of a monofocal intraocular lens (IOL), followed by implantation of the Hydrus Microstent.


Eligibility

Min Age: 45 Years

Inclusion Criteria3

  • An operable, age-related cataract with best corrected visual acuity (BCVA) of 20/40 or worse;
  • Diagnosis of primary open angle glaucoma treated with no more than 4 topical hypotensive medications;
  • Optic nerve appearance characteristic of glaucoma;

Exclusion Criteria6

  • Closed angle forms of glaucoma;
  • Congenital or developmental glaucoma;
  • Secondary glaucoma;
  • Use of more than 4 ocular hypotensive medications;
  • Previous argon laser trabeculoplasty, trabeculectomy, tube shunts, or any other prior filtration or cilioablative surgery;
  • Prior surgery with implanted device or other surgery involving the trabecular meshwork or Schlemm's canal;

Interventions

DEVICEHydrus Microstent

Crescent-shaped nitinol device intended as a permanent implant to provide an outflow pathway for aqueous humor. The device is placed through the trabecular meshwork into Schlemm's canal immediately following placement of a monofocal IOL.

PROCEDURECataract surgery

Cataract surgery performed using standard anesthesia and phacoemulsification techniques

DEVICEMonofocal IOL

Commercially available monofocal intraocular lens as determined by the investigator


Locations(22)

Coastal Vision

Irvine, California, United States

Sacramento Eye Consultants

Sacramento, California, United States

Eye Center of Northern Colorado

Loveland, Colorado, United States

Jones Eye Center PC

Sioux City, Iowa, United States

Stiles Eyecare Excellence Cataracts and Glaucoma

Overland Park, Kansas, United States

Visionary Eye Doctors

Rockville, Maryland, United States

Fraser Eye Care Center

Fraser, Michigan, United States

Twin Cities Eye Consultants

Coon Rapids, Minnesota, United States

Midwest Vision Research Foundation

Chesterfield, Missouri, United States

Moyes Eye Center

Kansas City, Missouri, United States

Center for Sight

Las Vegas, Nevada, United States

Carolina Eye Associates PA

Southern Pines, North Carolina, United States

Cleveland Eye Clinic

Brecksville, Ohio, United States

Cincinnati Eye Institute

Cincinnati, Ohio, United States

Cincinnati Eye / Apex Eye

Mason, Ohio, United States

Scott & Christie and Associates, PC

Cranberry Township, Pennsylvania, United States

Texan Eye / Keystone Research

Austin, Texas, United States

Glaucoma Associates Of Texas

Dallas, Texas, United States

El Paso Eye Surgeons

El Paso, Texas, United States

Texas Eye Research Center

Hurst, Texas, United States

The Eye Institute of Utah

Salt Lake City, Utah, United States

Eye Centers Of Racine And Kenosha

Kenosha, Wisconsin, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT04553523


Related Trials