RecruitingPhase 2NCT04600089

Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI

A Randomized, Double-blind, Placebo-controlled, Study to Identify the Opioid-sparing Effects, and Pain-reduction Potential of Low Dose Ketamine on Patients Undergoing TEVAR Procedures Receiving NCI


Sponsor

Sam Tyagi

Enrollment

30 participants

Start Date

Dec 8, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The objective of this study is to identify the opioid-sparing effects, and pain-reduction potential of low dose, sub-dissociative ketamine on patients undergoing thoracic endovascular aortic repair (TEVAR) procedures receiving naloxone continuous infusion (NCI).


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Ketamine and a drug called Saline for people with descending aortic dissection, postoperative pain, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSaline

Saline infusion

DRUGKetamine

Continuous ketamine infusion at a dose of 0.2 mg/kg/hr, initiated at the induction of anesthesia and continued for 48 hours postoperatively.


Locations(1)

University of Kentucky Medical Center

Lexington, Kentucky, United States

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NCT04600089


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