Investigation of Subclinical Markers of Multiple Sclerosis

This study investigates early or very subtle signs of multiple sclerosis (MS) using specialized brain and nerve measurements in people who have mild, early-stage relapsing-remitting MS with low disability. The goal is to detect disease activity at a subclinical level — meaning changes happening in the nervous system before they cause obvious symptoms — which could help guide treatment decisions earlier. **You may be eligible if...** - You have a confirmed diagnosis of relapsing-remitting multiple sclerosis according to standard diagnostic criteria (2005 McDonald criteria) - Your disability level is mild (an EDSS score of 0 to 3.5 on a standard neurological scale) - You are willing to sign a consent form and follow study procedures **You may NOT be eligible if...** - You have metal implants or devices in your body (such as a pacemaker or certain dental work) that could interfere with imaging - You are currently pregnant - You have had a recent head injury - You are unwilling or unable to follow study procedures Talk to your doctor to see if this trial is right for you.