LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge)

This study is testing a surgical procedure to treat arm swelling (lymphedema) that developed after breast cancer treatment. Researchers want to see if transplanting lymph nodes from another part of the body into the affected arm can reduce swelling long-term. **You may be eligible if...** - You are a breast cancer survivor aged 18–75 - You finished all cancer treatment at least 3 years ago with no signs of cancer returning - You have persistent arm swelling (lymphedema) that doesn't go away with elevation or compression - You have completed a full course of physical therapy (decongestive therapy) for at least 12 weeks - You are healthy enough for surgery under general anesthesia - You have been consistently using compression garments **You may NOT be eligible if...** - You currently have active cancer or completed treatment less than 3 years ago - You cannot safely undergo surgery or general anesthesia - You have a blood clotting disorder or active infection in the arm - You are currently receiving chemotherapy or radiation - You are pregnant or breastfeeding - Your BMI is over 35 - You have significant kidney or liver problems Talk to your doctor to see if this trial is right for you.