Edema Clinical Trials

256 recruitingLast updated: June 18, 2026

There are 256 actively recruiting edema clinical trials across 60 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4, Early Phase 1. Top locations include St Louis, Missouri, United States, Paris, France, Budapest, Hungary. Updated daily from ClinicalTrials.gov.


Edema Trials at a Glance

256 actively recruiting trials for edema are listed on ClinicalTrialsFinder across 6 cities in 60 countries. The largest study group is Not Applicable with 98 trials, with the heaviest enrollment activity in St Louis, Paris, and Budapest. Lead sponsors running edema studies include Universitaire Ziekenhuizen KU Leuven, Centre Hospitalier Universitaire de Nice, and Abramson Cancer Center at Penn Medicine.

Treatments under study

About Edema Clinical Trials

Looking for clinical trials for Edema? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Edema trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Edema clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 256 trials

Recruiting
Phase 3

STOP-HAE: A Phase 3 Study of ADX-324 in HAE

Hereditary AngioedemaHereditary Angioedema - Type 1Hereditary Angioedema - Type 2+1 more
ADARx Pharmaceuticals, Inc.90 enrolled51 locationsNCT06960213
Recruiting
Phase 3

Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)Hereditary Angioedema - Type 1Hereditary Angioedema - Type 2+1 more
ADARx Pharmaceuticals, Inc.90 enrolled48 locationsNCT07428499
Recruiting
Phase 1Phase 2

A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated

Diabetic Macular Edema
Boehringer Ingelheim49 enrolled31 locationsNCT07553429
Recruiting
Phase 2

A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema

Macular Edema
Boehringer Ingelheim300 enrolled80 locationsNCT06962839
Recruiting
Phase 3

Study of IV Human Plasma-derived C1 Esterase Inhibitor Concentrate in Patients With Congenital C1-INH Deficiency for Treatment and Pre-procedure Preventing of Acute Hereditary Angioedema Attacks

Acute Hereditary Angio Edema
Octapharma124 enrolled21 locationsNCT06361537
Recruiting

A Real-World Study to Gain Clinical Insights Into Faricimab (FaReal Study)

Neovascular Age-related Macular DegenerationDiabetic Macular Edema
Hoffmann-La Roche850 enrolled59 locationsNCT06680817
Recruiting
Not Applicable

Home- vs Hospital-based Care of Anti-VEGF Treatment for Diabetic Macular Edema: Non-inferiority RCT

Diabetic Macular Edema
Zhongshan Ophthalmic Center, Sun Yat-sen University308 enrolled4 locationsNCT06610747
Recruiting
Not Applicable

The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema

Lymphedema, Breast Cancer
University Hospital, Basel, Switzerland280 enrolled36 locationsNCT05890677
Recruiting

A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE)

Hereditary Angioedemas
CSL Behring200 enrolled22 locationsNCT07001280
Recruiting
Phase 3

CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

Diabetic Macular Edema (DME)Diabetic Macular EdemaDME
EyePoint Pharmaceuticals, Inc.240 enrolled62 locationsNCT07449923
Recruiting
Not Applicable

Erector Spinae Block Versus Paravertebral Block on Chronic Pain After Mastectomy

Opioid UseMastectomy; LymphedemaChronic Pain+1 more
American University of Beirut Medical Center132 enrolled1 locationNCT07561411
Recruiting
Phase 3

COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

Diabetic Macular Edema (DME)Diabetic Macular EdemaDME
EyePoint Pharmaceuticals, Inc.240 enrolled65 locationsNCT07449936
Recruiting

DATA-INSIGHT is a Project That Looks at Health Data in Germany to Find Out How Many Patients Suffer From Eye Disease. The Project Also Explores New Ways to Collect and Use Publicly Available Healthcare Information.

Neovascular Age-related Macular Degeneration (nAMD); Diabetic Macular Edema (DME); Retinal Vein Occlusion (RVO)
Bayer50,000 enrolled1 locationNCT07308639
Recruiting
Phase 3

Donidalorsen Treatment in Children With Hereditary Angioedema

Hereditary Angioedema (HAE)
Ionis Pharmaceuticals, Inc.20 enrolled10 locationsNCT07298447
Recruiting
Not Applicable

Systolic Function and Weaning-induced Pulmonary Edema (SystoWean Study)

Mechanical Ventilation ComplicationPulmonary Edema
Centre Hospitalier Universitaire de Nice250 enrolled3 locationsNCT05226247
Recruiting
Not Applicable

Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials

Weaning Invasive Mechanical VentilationWeaning-induced Pulmonary EdemaWeaning Failure of Mechanical Ventilation+2 more
Centre Hospitalier Régional d'Orléans24 enrolled1 locationNCT06923267
Recruiting
Phase 3

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Corneal EdemaCorneal Endothelial DysfunctionFuchs Endothelial Corneal Dysfunction+1 more
Aurion Biotech120 enrolled12 locationsNCT07368959
Recruiting
Phase 1

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)

Diabetic Macular Edema
Genentech, Inc.93 enrolled8 locationsNCT07425522
Recruiting
Not Applicable

A Study to Learn About the C1-Inhibitor Function as Diagnosis for Hereditary Angioedema

Hereditary Angioedema (HAE)
Takeda514 enrolled1 locationNCT07293364
Recruiting
Phase 3

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

Macular Edema Secondary to Inflammation
Kodiak Sciences Inc600 enrolled56 locationsNCT06990399