Blood Pressure Reduction in Patients With Asymptomatic Aortic VALVE Stenosis

This study is testing whether lowering blood pressure in patients with moderate aortic valve narrowing (stenosis) — who do not yet have symptoms — can slow the progression of the valve disease and prevent complications. **You may be eligible if...** - You have moderate narrowing of your aortic heart valve (confirmed by echocardiogram) - Your systolic blood pressure is 127 mmHg or higher - Your heart pumping function is normal (ejection fraction ≥ 50%) - You are 18 or older - Women of childbearing age must use reliable contraception and have a negative pregnancy test **You may NOT be eligible if...** - You already have symptoms from your aortic valve disease (chest pain, fainting, shortness of breath) - You have significant dizziness or low blood pressure when standing - You are suspected to have secondary causes of high blood pressure - You are participating in another drug study - You are pregnant or may become pregnant without appropriate contraception Talk to your doctor to see if this trial is right for you.