A Master Protocol Empowering Mechanobiology Translation Research in Breast Cancer

This study is collecting breast tissue samples and data from breast cancer patients to study the physical forces (mechanobiology) within tumors — including how stiff or soft the tissue is — to better understand how cancer grows and spreads. This is a research collection study, not a treatment trial. **You may be eligible if...** - You are 18 or older - You have a confirmed or strongly suspected breast cancer diagnosis based on clinical and imaging findings - You are in reasonably good functional health (for certain study tiers) - You consent to tissue and data collection **You may NOT be eligible if...** - You have another active cancer or a cancer diagnosis or relapse within the past 5 years (except early skin cancers or in-situ cervical cancer) - You have HIV, Hepatitis B, or Hepatitis C infection - You are unable to comply with study procedures due to personal, social, or geographic reasons Talk to your doctor to see if this trial is right for you.