RecruitingNCT04654767

Inflammatory Profiling in Chronic Lung Disease


Sponsor

Ludwig Boltzmann Institute for Lung Vascular Research

Enrollment

60 participants

Start Date

Dec 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The aim of this study is to investigate the underlying inflammatory profile in patients with chronic lung disease and determine the association pulmonary hypertension.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study examines inflammation patterns in patients with chronic lung disease — specifically COPD or idiopathic pulmonary fibrosis (IPF) combined with pulmonary hypertension — who are undergoing a lung transplant. Samples are collected to better understand how inflammation affects outcomes. **You may be eligible if...** - You have COPD or IPF along with pulmonary hypertension - You are undergoing a lung transplant - You have signed informed consent **You may NOT be eligible if...** - You have not provided written informed consent - You have signs of active infection, such as pneumonia, tuberculosis, or an infection causing fluid around the lungs Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERTissue sampling

Blood collection via venipuncture into citrate- or ethylenediaminetetraacetic (EDTA)-containing vacutainer tubes and into serum tubes. Explant lung tissue obtained from patients that underwent lung transplantation. Non-transplanted donor lungs that had been harvested for transplantation, but not implanted because of size-reduction serve as controls.


Locations(1)

Division of Thoracic Surgery, Department of Surgery, Medical University of Vienna

Vienna, Austria

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NCT04654767


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