RecruitingNot ApplicableNCT04671771

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease


Sponsor

W.L.Gore & Associates

Enrollment

133 participants

Start Date

Dec 3, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of the CSP-2002 clinical trial is to evaluate the safety and effectiveness of the InnAVasc Arteriovenous Graft (IG) for hemodialysis (HD) access in patients with end-stage renal disease (ESRD). The primary study endpoints are: Primary Effectiveness Endpoint: The proportion of subjects with secondary patency at 6 months. Primary Safety Endpoint: The incidence of device-related adverse events of special interest (AESIs) through 6 months. Participants will be asked to sign an informed consent form. Once enrolled, they will be assessed to receive the study graft implant and asked to participate in periodic follow-up visits and assessments through 2 years following implant.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating a new type of device called the InnAVasc Arteriovenous (AV) Graft for patients with end-stage kidney disease (kidney failure) who need dialysis access. An AV graft is a small tube placed under the skin to connect an artery and vein, creating a reliable site for dialysis. Researchers want to assess its safety and effectiveness compared to existing grafts. **You may be eligible if you:** - Have end-stage kidney disease (kidney failure) and need a new way to access your blood vessels for dialysis - Are between 18 and 90 years old - Have suitable arm anatomy for the graft to be placed - Are able to take anti-clotting or antiplatelet medication after the procedure **You may NOT be eligible if you:** - Have a serious infection or other condition making surgery too risky - Have had major problems with previous grafts or arm veins that would prevent this procedure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEInnAVasc Arteriovenous Graft (IG) surgical implant

The InnAVasc Arteriovenous Graft (IG) is a hemodialysis vascular access graft, intended for implantation in the lower or upper arm using standard vascular techniques, in patients requiring hemodialysis


Locations(21)

AKDHC Medical Research Services, LLC

Phoenix, Arizona, United States

Sarasota Memorial Hospital

Sarasota, Florida, United States

University of South Florida

Tampa, Florida, United States

Piedmont Augusta

Augusta, Georgia, United States

University of Louisville

Louisville, Kentucky, United States

University of Maryland

Baltimore, Maryland, United States

Brigham & Women's Hospital

Boston, Massachusetts, United States

Rutgers

Newark, New Jersey, United States

Mount Sinai Hospital

New York, New York, United States

Northwell Health

New York, New York, United States

Montefiore Medical Center

The Bronx, New York, United States

Surgical Specialists of Charlotte

Charlotte, North Carolina, United States

Duke University Medical Center

Durham, North Carolina, United States

NC Heart and Vascular Research, LLC

Raleigh, North Carolina, United States

WakeMed

Raleigh, North Carolina, United States

Guthrie Clinic

Sayre, Pennsylvania, United States

Prisma Health- Upstate

Greenville, South Carolina, United States

Medical University of South Carolina

Orangeburg, South Carolina, United States

Baylor Heart and Vascular

Dallas, Texas, United States

Houston Methodist Hopsital

Houston, Texas, United States

University of Washington

Seattle, Washington, United States

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NCT04671771


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