Kidney Failure Clinical Trials

9 recruiting

Frequently Asked Questions

Common questions about Kidney Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 30 trials

Recruiting
Phase 1

A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function

Kidney DiseaseRenal ImpairmentRenal Insufficiency, Chronic+3 more
Eli Lilly and Company28 enrolled2 locationsNCT07426380
Recruiting
Phase 1

A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)

End Stage Renal DiseaseRenal ImpairmentChronic Kidney Failure
Merck Sharp & Dohme LLC24 enrolled1 locationNCT07348237
Recruiting
Not Applicable

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

HemodialysisEnd Stage Renal Disease (ESRD)Kidney Failure+1 more
W.L.Gore & Associates133 enrolled21 locationsNCT04671771
Recruiting
Not Applicable

Web-based Advance Care Planning Intervention for Patients With Kidney Failure on Dialysis: Pilot Testing of 'My Voice'

Kidney Failure, Chronic Therapy; Hemodialysis
Duke-NUS Graduate Medical School100 enrolled1 locationNCT07309367
Recruiting

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

Kidney Disease, ChronicKidney DiseasesKidney Failure
Wake Forest University Health Sciences5,000 enrolled18 locationsNCT03615235
Recruiting

A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation

Kidney DiseaseCytomegalovirus (CMV)Kidney Failure
Takeda10 enrolled25 locationsNCT06243731
Recruiting
Not Applicable

A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF)

Kidney Disease, ChronicFrailtyKidney Failure
Seven Oaks Hospital Chronic Disease Innovation Centre54 enrolled2 locationsNCT06343727
Recruiting
Phase 3

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Heart FailureDiabetes Mellitus, Type 1Diabetic Nephropathies+1 more
Alessandro Doria150 enrolled18 locationsNCT06217302
Recruiting
Phase 3

Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas)

Kidney FailureLiver Failure, ChronicKidney-Pancreas Failure
Dr. F. Köhler Chemie GmbH362 enrolled4 locationsNCT03627013
Recruiting

Physical Impairments in Children With Chronic Renal Failure

Chronic Kidney DiseasesChronic Kidney Failure
Izmir Democracy University25 enrolled1 locationNCT06981585
Recruiting
Not Applicable

DIALysis With EXpanded Solute Removal

Kidney DiseaseChronic Kidney Disease Requiring HemodialysisHemodialysis+5 more
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's4,800 enrolled1 locationNCT06660277
Recruiting
Not Applicable

Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease

Kidney InjuryRisk ReductionKidney Failure, Chronic+1 more
Odense University Hospital254 enrolled1 locationNCT05283512
Recruiting
Not Applicable

First-in-human Study to Examine Safety of a New Peritoneal Dialysis Device (WEAKID) in End-stage Kidney Disease Patients

Chronic Kidney DiseasesRenal Insufficiency, ChronicKidney Failure, Chronic
UMC Utrecht12 enrolled3 locationsNCT06314503
Recruiting
Not Applicable

Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

Kidney Failure, ChronicHyperphosphatemia
The University of Queensland3,600 enrolled115 locationsNCT03573089
Recruiting
Phase 1Phase 2

CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk

Kidney FailureEnd Stage Renal DiseaseKidney Tumor+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053462
Recruiting
Phase 1Phase 2

Empagliflozin in ESKD - A Feasibility Study

Heart FailureKidney Failure, Chronic
University of Mississippi Medical Center24 enrolled2 locationsNCT05687058
Recruiting
Phase 1Phase 2

Roxadustat's Effect on Heart, Nutrition, and Inflammation in Hemodialysis Patients

Cardiovascular Diseases (CVD)Kidney Failure, ChronicMalnutrition-Inflammation Syndrome+1 more
Mansoura University46 enrolled1 locationNCT06903559
Recruiting
Phase 1Phase 2

Roxadustat for Bone and Neuropsychiatric Aspects in Hemodialysis Patients

Depression Anxiety DisorderKidney Failure, ChronicAnemia in End Stage Renal Disease
Mansoura University46 enrolled1 locationNCT06917950
Recruiting
Not Applicable

Effects of Royal Jelly Supplementation in Chronic Kidney Disease

HemodialysisOxidative StressKidney Failure, Chronic
Universidade Federal Fluminense30 enrolled1 locationNCT06438445
Recruiting

Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)

Kidney DiseasesDiabetic NephropathyKidney Failure, Chronic+2 more
The Rogosin Institute2,000 enrolled1 locationNCT01802034