Kidney Failure Clinical Trials

48 recruitingLast updated: June 18, 2026

There are 48 actively recruiting kidney failure clinical trials across 35 countries. Studies span Not Applicable, Phase 1, Phase 3, Phase 2, Phase 4, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, London, United Kingdom. Updated daily from ClinicalTrials.gov.


Kidney Failure Trials at a Glance

48 actively recruiting trials for kidney failure are listed on ClinicalTrialsFinder across 6 cities in 35 countries. The largest study group is Not Applicable with 16 trials, with the heaviest enrollment activity in Boston, New York, and London. Lead sponsors running kidney failure studies include The University of Queensland, Mansoura University, and Helsinki University Central Hospital.

Browse kidney failure trials by phase

Treatments under study

About Kidney Failure Clinical Trials

Looking for clinical trials for Kidney Failure? There are currently 26 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Kidney Failure trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Kidney Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 48 trials

Recruiting
Early Phase 1

Tolerance Through Mixed Chimerism (Sip-Tego)

Kidney FailureTransplant Recipient (Kidney)Immunosuppresion+2 more
Tatsuo Kawai, MD, PhD12 enrolled1 locationNCT06972069
Recruiting
Phase 1Phase 2

Immunological Reset to Enable Access to Hla-compatible Kidney Transplantation in Highly Sensitized Patients (RESET)

Kidney TransplantationKidney Failure, ChronicAlloimmunization+3 more
Hospital Universitari Vall d'Hebron Research Institute10 enrolled1 locationNCT07607197
Recruiting
Phase 1

A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)

End Stage Renal DiseaseRenal ImpairmentChronic Kidney Failure
Merck Sharp & Dohme LLC24 enrolled3 locationsNCT07348237
Recruiting

Effect of Protein Dosage on Persistent Acute Renal Failure in Critically Ill Patients.

Critical IllnessAcute Kidney FailureNutritional Support+2 more
Hospital Italiano de Buenos Aires344 enrolled6 locationsNCT07631221
Recruiting
Phase 1

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

Kidney TransplantKidney FailureEnd Stage Renal Failure on Dialysis
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled3 locationsNCT06056102
Recruiting
Not Applicable

Effects of Royal Jelly Supplementation in Chronic Kidney Disease

HemodialysisOxidative StressKidney Failure, Chronic
Universidade Federal Fluminense30 enrolled1 locationNCT06438445
Recruiting
Not Applicable

Effects of Sedation, TEmperature and Pressure After Cardiac Arrest and REsuscitation on Major Adverse Kidney Events (STEPCARE-MAKE)

TemperatureBlood PressureCardiac Arrest (CA)+9 more
Helsinki University Central Hospital3,500 enrolled52 locationsNCT07579390
Recruiting
Not Applicable

INCremental Dialysis to Improve Health Outcomes in People Starting Haemodialysis (INCH-HD)

Kidney Failure
The University of Queensland372 enrolled18 locationsNCT04932148
Recruiting
Not Applicable

Kidney Transplant Improvement Through New Exercise Training to Increase Capacity

Kidney FailureKidney TransplantationRenal Insufficiency, Chronic+7 more
University of Pennsylvania60 enrolled1 locationNCT07446296
Recruiting

International (Pediatric) Peritoneal Biobank

HealthyKidney Failure, ChronicTransplantation+1 more
Heidelberg University500 enrolled26 locationsNCT01893710
Recruiting
Not Applicable

A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF)

Kidney Disease, ChronicFrailtyKidney Failure
Seven Oaks Hospital Chronic Disease Innovation Centre54 enrolled2 locationsNCT06343727
Recruiting

Kidney Precision Medicine Project

Chronic Kidney DiseasesType 1 Diabetes (T1D)Kidney Failure, Acute+12 more
Icahn School of Medicine at Mount Sinai1,000 enrolled13 locationsNCT04334707
Recruiting
Phase 3

Shingrix in Renal Transplant Recipients

Kidney FailureKidney TransplantationKidney Failure, Chronic+2 more
University of Colorado, Denver132 enrolled4 locationsNCT04128189
Recruiting
Phase 3

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Heart FailureDiabetes Mellitus, Type 1Diabetic Nephropathies+1 more
Alessandro Doria150 enrolled19 locationsNCT06217302
Recruiting

Renal and Hepatic Abnormal Doppler Patterns in Trauma

Trauma patientsKidney DiseaseKidney Failure+3 more
Azienda Usl di Bologna350 enrolled1 locationNCT07492511
Recruiting
Not Applicable

STarting incrEmental Prescription of Peritoneal Dialysis

Kidney FailurePeritoneal Dialysis (PD)
The University of Queensland224 enrolled6 locationsNCT06642597
Recruiting
Phase 1

A Study of Eloralintide (LY3841136) in Participants With Renal Impairment and in Participants With Normal Renal Function

Kidney DiseaseRenal ImpairmentRenal Insufficiency, Chronic+3 more
Eli Lilly and Company28 enrolled2 locationsNCT07426380
Recruiting
Not Applicable

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

HemodialysisEnd Stage Renal Disease (ESRD)Kidney Failure+1 more
W.L.Gore & Associates133 enrolled21 locationsNCT04671771
Recruiting
Not Applicable

Erector Spinae Plane Block vs Quadratus Lumborum Block for Laparoscopic Nephrectomy

Kidney DiseasesKidney Failure
Istanbul Medipol University Hospital60 enrolled1 locationNCT06298227
Recruiting
Not Applicable

Web-based Advance Care Planning Intervention for Patients With Kidney Failure on Dialysis: Pilot Testing of 'My Voice'

Kidney Failure, Chronic Therapy; Hemodialysis
Duke-NUS Graduate Medical School100 enrolled1 locationNCT07309367