Kidney Failure Clinical Trials

22 recruiting

Kidney Failure Trials at a Glance

37 actively recruiting trials for kidney failure are listed on ClinicalTrialsFinder across 6 cities in 31 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Boston, New York, and Baltimore. Lead sponsors running kidney failure studies include The University of Queensland, Centre Hospitalier Departemental Vendee, and Alessandro Doria.

Browse kidney failure trials by phase

Treatments under study

About Kidney Failure Clinical Trials

Looking for clinical trials for Kidney Failure? There are currently 22 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Kidney Failure trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Kidney Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 37 trials

Recruiting

International (Pediatric) Peritoneal Biobank

HealthyKidney Failure, ChronicTransplantation+1 more
Heidelberg University500 enrolled26 locationsNCT01893710
Recruiting
Not Applicable

A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF)

Kidney Disease, ChronicFrailtyKidney Failure
Seven Oaks Hospital Chronic Disease Innovation Centre54 enrolled2 locationsNCT06343727
Recruiting

Kidney Precision Medicine Project

Chronic Kidney DiseasesType 1 Diabetes (T1D)Kidney Failure, Acute+12 more
Icahn School of Medicine at Mount Sinai1,000 enrolled13 locationsNCT04334707
Recruiting
Phase 3

Shingrix in Renal Transplant Recipients

Kidney FailureKidney TransplantationKidney Failure, Chronic+2 more
University of Colorado, Denver132 enrolled4 locationsNCT04128189
Recruiting
Phase 1

A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)

Chronic Kidney Failure
Merck Sharp & Dohme LLC24 enrolled3 locationsNCT07348237
Recruiting
Phase 3

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Diabetic NephropathiesKidney Failure, Chronic
Alessandro Doria150 enrolled19 locationsNCT06217302
Recruiting
Not Applicable

STarting incrEmental Prescription of Peritoneal Dialysis

Kidney FailurePeritoneal Dialysis (PD)
The University of Queensland224 enrolled6 locationsNCT06642597
Recruiting
Not Applicable

Erector Spinae Plane Block vs Quadratus Lumborum Block for Laparoscopic Nephrectomy

Kidney DiseasesKidney Failure
Istanbul Medipol University Hospital60 enrolled1 locationNCT06298227
Recruiting
Not Applicable

A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

HemodialysisEnd Stage Renal Disease (ESRD)Kidney Failure+1 more
W.L.Gore & Associates133 enrolled21 locationsNCT04671771
Recruiting
Not Applicable

Web-based Advance Care Planning Intervention for Patients With Kidney Failure on Dialysis: Pilot Testing of 'My Voice'

Kidney Failure, Chronic Therapy; Hemodialysis
Duke-NUS Graduate Medical School100 enrolled1 locationNCT07309367
Recruiting

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

Kidney Disease, ChronicKidney DiseasesKidney Failure
Wake Forest University Health Sciences5,000 enrolled18 locationsNCT03615235
Recruiting

A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation

Kidney DiseaseCytomegalovirus (CMV)Kidney Failure
Takeda10 enrolled25 locationsNCT06243731
Recruiting
Phase 1

CAR-T Cell Therapy for Desensitization in Kidney Transplantation

Kidney TransplantKidney FailureEnd Stage Renal Failure on Dialysis
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled3 locationsNCT06056102
Recruiting
Early Phase 1

Tolerance Through Mixed Chimerism (Sip-Tego)

Kidney FailureTransplant Recipient (Kidney)Immunosuppresion+2 more
Tatsuo Kawai, MD, PhD12 enrolled1 locationNCT06972069
Recruiting
Phase 3

Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas)

Kidney FailureLiver Failure, ChronicKidney-Pancreas Failure
Dr. F. Köhler Chemie GmbH362 enrolled4 locationsNCT03627013
Recruiting

Physical Impairments in Children With Chronic Renal Failure

Chronic Kidney DiseasesChronic Kidney Failure
Izmir Democracy University25 enrolled1 locationNCT06981585
Recruiting
Not Applicable

DIALysis With EXpanded Solute Removal

Kidney DiseaseChronic Kidney Disease Requiring HemodialysisHemodialysis+5 more
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's4,800 enrolled1 locationNCT06660277
Recruiting
Not Applicable

First-in-human Study to Examine Safety of a New Peritoneal Dialysis Device (WEAKID) in End-stage Kidney Disease Patients

Chronic Kidney DiseasesRenal Insufficiency, ChronicKidney Failure, Chronic
UMC Utrecht12 enrolled3 locationsNCT06314503
Recruiting
Not Applicable

Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)

Kidney Failure, ChronicHyperphosphatemia
The University of Queensland3,600 enrolled115 locationsNCT03573089
Recruiting
Phase 1Phase 2

Empagliflozin in ESKD - A Feasibility Study

Heart FailureKidney Failure, Chronic
University of Mississippi Medical Center24 enrolled2 locationsNCT05687058