RecruitingNot ApplicableNCT04678635

Chronic Transcranial Direct Current Stimulation in Patients With Systemic Autoimmune Myopathies


Sponsor

University of Sao Paulo

Enrollment

40 participants

Start Date

Dec 12, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

Systemic autoimmune myopathies are rheumatic diseases that affect the striatum skeletal muscles. The transcranial direct current stimulation technique has been frequent, for example, in patients with ischemic stroke or for the optimization of muscular performance in athletes. However, to date, there are no studies evaluating this technique in patients with systemic autoimmune myopathies. Therefore, the main objective of the present prospective, randomized, double-blind, placebo-controlled study is to evaluate the safety and efficacy of the application of chronic transcranial direct current stimulation sessions - associated with aerobic exercises - in the patients with systemic autoimmune myopathies.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is evaluating the use of transcranial direct current stimulation (tDCS) — a non-invasive brain stimulation technique — in people with systemic autoimmune myopathies (SAM). SAM includes conditions like polymyositis and dermatomyositis, which cause muscle weakness and pain. Researchers are investigating whether tDCS can help reduce pain or improve muscle function when applied repeatedly over time. You may be eligible if: - You have been diagnosed with a systemic autoimmune myopathy according to EULAR/ACR 2017 criteria or Connors et al. classification criteria - You are between 18 and 70 years old You may NOT be eligible if: - You have an active cancer (neoplasia) - You have a heart pacemaker or metallic visceral clips - You have an active infection (HIV, HTLV-1, Hepatitis, etc.) - You are pregnant - You have a history of seizures or epilepsy Talk to your rheumatologist about whether brain stimulation therapy might be appropriate given your current treatment status and overall health.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERChronic transcranial direct current stimulation

Chronic transcranial direct current stimulation


Locations(1)

Samuel K Shinjo

São Paulo, São Paulo, Brazil

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NCT04678635


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