RecruitingNCT04682483

Cardiogenic Shock Working Group Registry


Sponsor

Tufts Medical Center

Enrollment

5,000 participants

Start Date

Dec 4, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

The Cardiogenic Shock Working Group is a multicenter registry where we collect de-identified clinical variables from the medical records and follow-up phone calls of shock patients from multiple institutions and centralize this data to a single registry for analysis of clinical outcomes.


Eligibility

Min Age: 18 Years

Inclusion Criteria10

  • Patients must have cardiogenic shock.
  • Cardiogenic shock is defined by at least one of the two categories below:
  • At least 2 of the following concurrently at any point during the index hospitalization:
  • Cardiac Index \< 2.2
  • PAPI \< 1.0
  • Cardiac Power Output ≤ 0.6
  • MAP \< 60mmHg or a \>30mmHg drop in MAP from baseline
  • SBP \< 90mmHg or a \>30mmHg drop in SBP from baseline
  • Pulse \> 100
  • Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target.

Interventions

DRUGVasopressor

The vasopressors include phenylephrine, norepinephrine, epinephrine, dopamine and vasopressin.

DRUGInotrope

Inotropes include dobutamine and milrinone.

DEVICEAcute Mechanical Circulatory Support Devices

Acute Mechanical Circulatory Support devices include ECMO (VV), ECMO (VA), Impella CP, Impella 2.5, Impella 5.0, Impella 5.5, Impella RP, IABP, Centrimag, Tandem Heart and ProTek Duo.


Locations(16)

Cleveland Clinic Florida

Weston, Florida, United States

Northwestern Medicine

Chicago, Illinois, United States

University of Chicago

Chicago, Illinois, United States

Maine Medical Center

Portland, Maine, United States

Tufts Medical Center

Boston, Massachusetts, United States

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States

Hackensack Meridian Health

Hackensack, New Jersey, United States

Columbia University Irving Medical Center

New York, New York, United States

Providence St. Vincent Heart Clinic

Portland, Oregon, United States

Allegheny General Hospital

Pittsburgh, Pennsylvania, United States

University Of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Baylor Scott & White Advanced Heart Failure Clinic

Dallas, Texas, United States

University of Texas Medical Branch

Galveston, Texas, United States

Houston Methodist Hospital

Houston, Texas, United States

Inova Health System

Falls Church, Virginia, United States

University of Washington Medical Center

Seattle, Washington, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT04682483


Related Trials