RecruitingNot ApplicableNCT04694534

Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients

e-SEP Cognition: Effectiveness of a Remediation Program Via a "Serious Game" on the Cognitive Functions of Multiple Sclerosis Patients: Controlled, Randomized, Multicentric Trial


Sponsor

Lille Catholic University

Enrollment

150 participants

Start Date

Oct 8, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The main goal of this study is to assess the effectiveness of a cognitive remediation program based on a "serious game" on the information processing speed evolution and the process of learning via episodic memory in multiple sclerosis patients.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether a brain-training computer game (called a "serious game") can improve thinking and memory problems (cognitive difficulties) in adults with multiple sclerosis (MS). Participants play the game online at home over several weeks. **You may be eligible if...** - You are between 18 and 65 years old - You have relapsing-remitting or progressive MS (diagnosed using McDonald's criteria) - You have noticed memory or thinking problems, confirmed by neuropsychological testing - You have not had a relapse in the past 6 weeks - You have access to the internet at home - You are not taking antipsychotic medications **You may NOT be eligible if...** - Your cognitive difficulties are severe (failing many different cognitive tests) - You are currently in neuropsychological therapy - You had a steroid treatment less than 4 weeks ago - You are not able to use a computer or internet Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTSerious game

The serious game is accessible via an online platform, on a tablet: 4 20-minutes activities sessions per week must be carried out. The program format in the serious game form makes possible to simultaneously understand a large number of cognitive functions.

DIAGNOSTIC_TESTUsual HAS care

The control group patients will follow the care they need, according to the HAS recommendations. Non-specific cognitive activities notebooks will be provided to them. They will be instructed to perform the 4 20-minutes sessions per week for 4 months.


Locations(6)

CH Arras

Arras, Hauts-de-France, France

CH LENS

Lens, Hauts-de-France, France

CHRU

Lille, Hauts-de-France, France

Saint Vincent hospital

Lille, Hauts-de-France, France

Saint-Philibert hospital

Lomme, Nord, France

Charles Nicolle Hospital

Rouen, Normandy, France

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NCT04694534


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