RecruitingNCT04705766

KIDney Injury in Times of COVID-19 (KIDCOV)

The KIDCOV Study: ASSESSMENT of SARS-CoV-2 Without HOSPITALIZATION as a RISK FACTOR for ACUTE KIDNEY INJURY

Sponsor

University of California, San Francisco

Enrollment

2,000 participants

Start Date

Mar 1, 2021

Study Type

OBSERVATIONAL

Conditions

COVID19 Acute Kidney Injury Kidney Injury Corona Virus Infection SARS-CoV Infection

Summary

There is an unmet need to evaluate the impact of sub-clinical/mild COVID19 disease in the outpatient setting on prevalent and incident renal injury, as this data is currently unavailable. To capture the diversity of race/ethnic risk and COVID19 related municipal shelter-in-place guidance, the investigators will enroll COVID19-negative and COVID19-positive samples balanced by race/ethnicity from 3 different states, California, Michigan, and Illinois. Study endpoints will be assayed from urine samples mailed to the study team at 2, 6, and 12 months after their date of PCR test, with no requirement for these individuals to leave their homes to participate.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

KIDCOV is a study tracking kidney injury outcomes in people who have tested positive or negative for COVID-19. COVID-19 is known to affect multiple organs, including the kidneys. Acute kidney injury (AKI) — a sudden decline in kidney function — is more common in COVID-19 patients, particularly those who are hospitalized. This study follows patients for several months after their COVID-19 test to understand how kidney function changes over time and what factors predict who is at risk. The study enrolls adults 18 and older who have had a PCR-based COVID-19 test at a participating medical center within the past 4 weeks. Both people who tested positive and those who tested negative are included for comparison. You may be eligible if: - You are 18 or older - You had a PCR-based COVID-19 test at a participating medical center in the past 4 weeks - You are willing to provide contact details and follow-up information You may NOT be eligible if: - You were hospitalized within 4 weeks after your COVID-19 test - You have a history of kidney transplant - You have a history of dialysis - You are unable or unwilling to provide written informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERUrine Collection

A urine collection kit will be mailed to subjects' residence at 3 different timepoints over the course of 1 year to be returned to study team, upon which KIT score and other biomarkers will be assessed as outlined in the study design.