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RecruitingNCT04706234

Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

Prospective Observational Study for the Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

Sponsor

Kliniken Beelitz GmbH

Enrollment

350 participants

Start Date

Sep 1, 2017

Study Type

OBSERVATIONAL

Conditions

Multiple System AtrophyParkinson DiseaseMotor Neuron DiseaseProgressive Supranuclear PalsyNeurodegenerative Diseases

Summary

This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is systematically evaluating swallowing and voice (laryngopharyngeal) function in patients with neurodegenerative diseases, including Parkinson's disease, multiple system atrophy (MSA), progressive supranuclear palsy (PSP), motor neurone disease, and others. The goal is to improve detection and management of swallowing difficulties in these conditions. **You may be eligible if...** - You have a diagnosis of Parkinson's disease, MSA, PSP, motor neurone disease, or another neurodegenerative condition - You have undergone laryngopharyngeal (throat/voice) assessment as part of your clinical care **You may NOT be eligible if...** - You have not had a laryngopharyngeal assessment - You have a condition not related to neurodegeneration Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(16)

Department of Neurology and Department of ENT, Medical University Innsbruck

Innsbruck, Tyrol, Austria

Department of Neurology, Medical University of Ulm

Ulm, Baden-Wurttemberg, Germany

Movement Disorders Hospital - Kliniken Beelitz

Beelitz-Heilstätten, Brandenburg, Germany

Department of Neurology, Medical School Hannover

Hanover, Lower Saxony, Germany

Department of Neurology, University Hospital Münster

Münster, North Rhine-Westphalia, Germany

Department of Neurology, University Hospital Carl Gustav Carus

Dresden, Saxony, Germany

Department of Neueology Asklepios Klinik Stadtroda

Stadtroda, Thuringia, Germany

Asklepios Fachklinikum Stadtroda

Stadtroda, Thuringia, Germany

Asklepios Klinik Barmbek

Hamburg, Germany

Department of Neurology Asklepios Klinik Barmbek

Hamburg, Germany

Department of Neurology, Movement Disorders Unit, Medical Center Tel Aviv

Tel Aviv, Israel

IRCCS Istituto delle Scienze Neurologiche, Azienda USL di Bologna

Bologna, Italy

Department of Neurology, Gifu University Graduate School of Medicine

Gifu, Japan

Department of Neurology, Medical University Warsaw

Warsaw, Poland

Department of Neurology SNUCM

Seoul, South Korea

Unidad de Parkinson y Trastornos del Movimiento Instituto Clínic de Neurociencias, Hospital Clinic de Barcelona

Barcelona, Catalonia, Spain

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NCT04706234

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