Progressive Supranuclear Palsy Clinical Trials

20 recruiting

Progressive Supranuclear Palsy Trials at a Glance

23 actively recruiting trials for progressive supranuclear palsy are listed on ClinicalTrialsFinder across 6 cities in 18 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Toronto, Boston, and Rochester. Lead sponsors running progressive supranuclear palsy studies include Mayo Clinic, University Health Network, Toronto, and Baycrest.

Browse progressive supranuclear palsy trials by phase

Treatments under study

About Progressive Supranuclear Palsy Clinical Trials

Looking for clinical trials for Progressive Supranuclear Palsy? There are currently 20 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Progressive Supranuclear Palsy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Progressive Supranuclear Palsy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Amyotrophic Lateral SclerosisFrontotemporal DementiaProgressive Supranuclear Palsy
National Institute of Neurological Disorders and Stroke (NINDS)360 enrolled1 locationNCT03225144
Recruiting
Not Applicable

The Swedish BioFINDER 2 Study

DementiaMultiple System AtrophyAlzheimer Disease+10 more
Skane University Hospital2,950 enrolled2 locationsNCT03174938
Recruiting

Synaptic Loss in Multiple System Atrophy

Multiple System AtrophyProgressive Supranuclear Palsy (PSP)
University of Exeter36 enrolled1 locationNCT05121012
Recruiting

Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging

Multiple System AtrophyParkinson DiseaseProgressive Supranuclear Palsy
University of Texas Southwestern Medical Center90 enrolled1 locationNCT03872102
Recruiting

The CurePSP Genetics Program

PSPPSP - Progressive Supranuclear PalsyCorticobasal Syndrome+4 more
Massachusetts General Hospital1,000 enrolled1 locationNCT06647641
Recruiting
Early Phase 1

First-in-Human Study for the Safety and Evaluation of Two 4R Tau Ligands as Potential PET Radioligands for Imaging Tau Protein in the Brain

Healthy ParticipantsProgressive Supranuclear Palsy (PSP)
Invicro24 enrolled1 locationNCT07348276
Recruiting
Not Applicable

A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy

Progressive Supranuclear Palsy
Mayo Clinic332 enrolled1 locationNCT02605785
Recruiting
Not Applicable

tDCS as Treatment for Motor Function

Parkinson DiseaseProgressive Supranuclear PalsyCortical Basal Ganglionic Degeneration
Baycrest20 enrolled1 locationNCT07291687
Recruiting

Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling

DementiaAlzheimer DiseaseParkinson Disease+7 more
University Health Network, Toronto500 enrolled4 locationsNCT06529744
Recruiting
Not Applicable

Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology

Myasthenia GravisHuntington DiseaseNeuromuscular Diseases+9 more
Centre Hospitalier Universitaire de Liege300 enrolled1 locationNCT07136844
Recruiting

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

Amyotrophic Lateral SclerosisCorticobasal Degeneration (CBD)Progressive Supranuclear Palsy (PSP)+11 more
Mayo Clinic2,100 enrolled27 locationsNCT04363684
Recruiting

Gait Analysis in Neurological Disease

Multiple System AtrophyHuntington DiseaseCorticobasal Degeneration+5 more
Beth Israel Deaconess Medical Center120 enrolled1 locationNCT02994719
Recruiting
Not Applicable

Neurologic Stem Cell Treatment Study

Cognitive ImpairmentDementiaTraumatic Brain Injury+23 more
MD Stem Cells500 enrolled3 locationsNCT02795052
Recruiting

Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases

Multiple System AtrophyParkinson DiseaseMotor Neuron Disease+2 more
Kliniken Beelitz GmbH350 enrolled16 locationsNCT04706234
Recruiting

Diagnosing Frontotemporal Lobar Degeneration

Corticobasal SyndromeProgressive Supranuclear PalsySemantic Dementia+3 more
University Health Network, Toronto100 enrolled1 locationNCT02964637
Recruiting

NYSCF Scientific Discovery Biobank

Ovarian CancerCervical CancerDiabetes Mellitus+26 more
New York Stem Cell Foundation Research Institute10,000 enrolled1 locationNCT06203106
Recruiting
Phase 2

The NADAPT Study: a Randomized Double-blind Trial of NAD Replenishment Therapy for Atypical Parkinsonism

Multiple System AtrophyCorticobasal SyndromeProgressive Supranuclear Palsy
Haukeland University Hospital330 enrolled3 locationsNCT06162013
Recruiting
Not Applicable

The Use of the CUE1/CUE1+ in People With Parkinson's Disease and Related Disorders

Multiple System AtrophyCorticobasal DegenerationDystonia+5 more
Queen Mary University of London70 enrolled1 locationNCT06174948
Recruiting

Utilisation of Health Services and Quality of Life in Patients With Atypical Parkinsonian Syndromes

Multiple System AtrophyProgressive Supranuclear PalsyCortico Basal Degeneration
University Hospital Southampton NHS Foundation Trust198 enrolled1 locationNCT06645626
Recruiting

Biomarkers in Parkinsonian Syndromes

Multiple System AtrophyParkinson DiseaseProgressive Supranuclear Palsy+2 more
Non-profit organization for scientific research in Parkinson's disease and related disorders200 enrolled1 locationNCT06501469