RecruitingNCT04732273

The Swiss Childhood Cancer Survivor Study - Follow-up (SCCSS-FollowUp)


Sponsor

University of Bern

Enrollment

3,000 participants

Start Date

Jun 20, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The SCCSS-FollowUp is a national, multicenter cohort study designed to investigate late effects in childhood cancer survivors in a prospective and longitudinal way. The study is embedded in regular follow-up care and inclusion in the study takes place in a step-wise approach. The investigators collect data from clinical examinations, laboratory and functional tests, and questionnaires to learn more about late effects of childhood cancer treatments.


Eligibility

Inclusion Criteria6

  • This prospective cohort study is based on the Childhood Cancer Registry (ChCR), a national, population-based cancer registry that includes all children and adolescents in Switzerland who were diagnosed with cancer at age 0-20 years. It includes patients diagnosed with leukemia, lymphoma, central nervous system tumors, and malignant solid tumors or Langerhans cell histiocytosis.
  • Registered in the Childhood Cancer Registry (ChCR) or treated and followed-up in a Swiss pediatric oncology (SPOG) clinic, but not registered in the ChCR because of residency in neighboring countries
  • Diagnosed at age 0 - 20 years
  • Childhood cancer treatment completed
  • All age categories at time of inclusion in the study (children, adolescents, adults)
  • Written informed consent

Exclusion Criteria1

  • Childhood cancer survivors in a palliative or relapsed situation where no follow-up examinations are foreseen.

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Interventions

OTHERPhysical examination, diagnostic tests, laboratory tests

Physical examination, diagnostic tests depending on examined organ system (e.g. lung function test, echocardiography, audiometry), and laboratory tests (e.g. kidney parameter, hormonal levels).

OTHERPersonal history, questionnaire

Personal history and focused questionnaires per organ system including symptoms, medication use, physical activity, and general wellbeing.


Locations(3)

University Childen's Hospital Basel

Basel, Switzerland

University Children's Hospital Bern

Bern, Switzerland

University Hospital Geneva

Geneva, Switzerland

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